| Cardiopulmonary exercise testing in evaluation of patients of chronic obstructive pulmonary disease. | |
| | |
MedLine Citation:
|
PMID: 21545069 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
BACKGROUND: Objective assessment of severity in patients with chronic obstructive pulmonary disease (COPD) is mainly limited to pulmonary function testing performed at rest. But, accurate assessment of exercise capacity in patients with COPD may be possible with cardiopulmonary exercise testing (CPET). METHODS: Forty-three patients with stable COPD were included and were divided into three groups based upon the spirometry data as per the Global Initiative for Obstructive Lung Disease (GOLD) guidelines as follows: Group A: mild COPD, Group B: moderately severe COPD and Group C: severe COPD. Symptom-limited CPET was performed using treadmill on incremental continuous ramp protocol in all of them. RESULTS: Five patients (11.6%) had mild COPD; 16 (37.2%) had moderately severe COPD and the remaining 22 (51.6%) patients had severe COPD. Anaerobic threshold was attained in all the 43 patients. The dominant symptom at peak exercise were dyspnoea (n = 19) and both dyspnoea and leg fatigue (n = 7). The other causes of exercise limitation included dyspnoea with significant oxygen desaturation (n = 6); and dyspnoea with severe oxygen desaturation (n = 2). Six patients complained only of leg fatigue at peak exercise. A significant correlation between forced expiratory volume in the first second (FEV1) percent predicted and the predicted maximum oxygen uptake (VO2 max % predicted) was observed in all the three groups (r = 0.39, p = 0.011) but with marked variability of peak VO2 for a given degree of airflow obstruction. Twenty-three (53.5%) patients with low anaerobic threshold (< 30%) were identified as potential group likely to benefit from exercise training for pulmonary rehabilitation. CONCLUSIONS: Cardiopulmonary exercise testing is useful to determine the causes of exercise limitation and to assess the maximal exercise capacity of patients with COPD. |
| | |
Authors:
|
A A Ganju; A B Fuladi; B O Tayade; N A Ganju |
Related Documents
:
|
9807649 - Fenfluramine challenge test as a marker of serotonin activity in patients with alzheime... 1729549 - Dual radioisotopic study: a technique for the evaluation of vasculogenic impotence. 12647959 - Influence of pulsation rate on udder health and teat thickness changes in dairy ewes. 1209159 - Compensation for geometric changes during monitoring of 133xe washout from subcutaneous... 1131119 - Physical and auditory specifications of third-octave clicks. 12447449 - The length of cooperative units on the thin filament in rabbit psoas muscle fibres. 12805079 - Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and i... 3942059 - Effects of isoproterenol and amiodarone and the role of exercise in initiation of circu... 10776889 - Cardiorespiratory and metabolic responses to exercise in hbsc sickle cell patients. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Indian journal of chest diseases & allied sciences Volume: 53 ISSN: 0377-9343 ISO Abbreviation: Indian J Chest Dis Allied Sci Publication Date: 2011 Apr-Jun |
Date Detail:
|
Created Date: 2011-05-06 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7612044 Medline TA: Indian J Chest Dis Allied Sci Country: India |
Other Details:
|
Languages: eng Pagination: 87-91 Citation Subset: IM |
Affiliation:
|
Department of Chest Medicine and Tuberculosis, Government Medical College, Nagpur (Maharashtra), India. anuganju@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Sildenafil improves six-minute walk distance in chronic obstructive pulmonary disease: a randomised,...
Next Document: Initial experience of endobronchial silicon stents from a tertiary care centre in North India.