Document Detail

Cardiopulmonary bypass in sickle cell anaemia. Report of five cases.
MedLine Citation:
PMID:  2019634     Owner:  NLM     Status:  MEDLINE    
Five patients with sickle cell haemoglobinopathies underwent open heart surgery. At the start of the cardiopulmonary bypass the patient's circulating blood volume was separately drained into a bag, spun down and retransfused into the patient at the end of the operation. Moderate hypothermia, aortic cross clamping, topical hypothermia and cold crystalloid cardioplegia were used in all patients. None of the patients had transfusions in the postoperative period. No macroscopic or microscopic evidence of haemolysis were seen, nor haematuria or other clinical evidence of sickling. There was no evidence of wound infection and all were discharged home at a mean of 12.6 days. It is concluded that in cases of sickle cell anaemia exchange transfusion at the beginning of cardiopulmonary bypass followed by retransfusion of the red cell free blood can be used safely, permitting the performance of standard open heart procedures.
S Balasundaram; C G Duran; Z al-Halees; M Kassay
Related Documents :
18473244 - An estimation of the incidence and demographic picture of the major hemoglobinopathies ...
19663084 - Hepatobiliary abnormalities in pediatric patients with sickle cell disease.
11099664 - Transfusion of washed and centrifuged shed rbcs during maxillofacial surgery affects cy...
17655594 - Prophylactic red blood cell exchange for prevention of severe immune hemolysis in minor...
1834004 - Stroke prevention in nonvalvular atrial fibrillation.
18234004 - High sensitivity crp levels predict atrial tachyarrhythmias in rheumatic mitral stenosis.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  32     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:    1991 Mar-Apr
Date Detail:
Created Date:  1991-05-30     Completed Date:  1991-05-30     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  271-4     Citation Subset:  IM    
Department of Cardiovascular Diseases, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anemia, Sickle Cell / complications*
Cardiopulmonary Bypass / methods*
Child, Preschool
Exchange Transfusion, Whole Blood*
Heart Defects, Congenital / complications,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Bovine internal thoracic artery graft. Successful use at urgent coronary bypass surgery.
Next Document:  Coronary-subclavian steal corrected with percutaneous transluminal angioplasty.