Document Detail


Cardiopulmonary bypass in sickle cell anaemia. Report of five cases.
MedLine Citation:
PMID:  2019634     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Five patients with sickle cell haemoglobinopathies underwent open heart surgery. At the start of the cardiopulmonary bypass the patient's circulating blood volume was separately drained into a bag, spun down and retransfused into the patient at the end of the operation. Moderate hypothermia, aortic cross clamping, topical hypothermia and cold crystalloid cardioplegia were used in all patients. None of the patients had transfusions in the postoperative period. No macroscopic or microscopic evidence of haemolysis were seen, nor haematuria or other clinical evidence of sickling. There was no evidence of wound infection and all were discharged home at a mean of 12.6 days. It is concluded that in cases of sickle cell anaemia exchange transfusion at the beginning of cardiopulmonary bypass followed by retransfusion of the red cell free blood can be used safely, permitting the performance of standard open heart procedures.
Authors:
S Balasundaram; C G Duran; Z al-Halees; M Kassay
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  32     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:    1991 Mar-Apr
Date Detail:
Created Date:  1991-05-30     Completed Date:  1991-05-30     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  271-4     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Diseases, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Anemia, Sickle Cell / complications*
Cardiopulmonary Bypass / methods*
Child
Child, Preschool
Exchange Transfusion, Whole Blood*
Female
Heart Defects, Congenital / complications,  surgery
Humans
Male

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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