Document Detail

Cardiopulmonary and behavioral effects of fentanyl-droperidol in cats.
MedLine Citation:
PMID:  3610779     Owner:  NLM     Status:  MEDLINE    
The combination of the narcotic fentanyl (0.4 mg/ml) and the tranquilizer droperidol (20 mg/ml) was injected into 12 healthy adult cats at a rate of 1 ml/9 kg of body weight, sc. Arterial blood pressure, heart rate, respiratory frequency, PaCO2, and PaO2, arterial pH (pHa), and rectal temperature were measured before and 30, 60, 90, and 120 minutes after injection of fentanyl-droperidol. Respiratory frequency was decreased significantly (P less than 0.05) and heart rate increased significantly (P less than 0.05) at all measurement intervals after drug administration. Observed decrements in arterial blood pressure were not significant. Arterial PO2, PCO2, and pH did not change significantly. A significant (P less than 0.05) decrease in body temperature was measured 90 minutes after drug administration. All cats were calm, tractable, and frequently assumed lateral recumbency after administration of fentanyl-droperidol. This maximal tranquil state was determined to be 30 to 60 minutes after drug administration.
J L Grandy; R B Heath
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  191     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  1987 Jul 
Date Detail:
Created Date:  1987-09-15     Completed Date:  1987-09-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  59-61     Citation Subset:  IM    
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MeSH Terms
Behavior, Animal / drug effects*
Blood Gas Analysis / veterinary
Blood Pressure / drug effects
Body Temperature / drug effects
Cats / physiology*
Droperidol / pharmacology*
Drug Combinations
Fentanyl / pharmacology*
Heart Rate / drug effects
Hydrogen-Ion Concentration
Respiration / drug effects
Reg. No./Substance:
0/Drug Combinations; 437-38-7/Fentanyl; 548-73-2/Droperidol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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