Document Detail

Cardiopulmonary exercise testing in cancer rehabilitation: a systematic review.
MedLine Citation:
PMID:  22452663     Owner:  NLM     Status:  MEDLINE    
This systematic review aims to get insight into the feasibility of cardiopulmonary exercise testing (CPET) in patients with cancer prior to a physical exercise programme. We will focus on quality (defined as the adherence to international guidelines for methods of CPET) and safety of CPET. Furthermore, we compare the peak oxygen uptake (·VO(2peak)) values of patients with cancer with reference values for healthy persons to put these values into a clinical perspective. A computer aided search with 'cardiopulmonary exercise testing' and 'cancer' using MEDLINE, EMBASE, Pedro, CINAHL® and SPORTDiscus™ was carried out. We included studies in which CPET with continuous gas exchange analysis has been performed prior to a physical exercise programme in adults with cancer. Twenty studies describing 1158 patients were eligible. Reported adherence to international recommendations for CPET varied per item. In most studies, the methods of CPET were not reported in detail. Adverse events occurred in 1% of patients. The percentage ·VO(2peak) of reference values for healthy persons varied between 65% and 89% for tests before treatment, between 74% and 96% for tests during treatment and between 52% and 117% for tests after treatment. Our results suggest that CPET is feasible and seems to be safe for patients with cancer prior to a physical exercise programme. We recommend that standard reporting and quality guidelines should be followed for CPET methods. The decreased ·VO(2peak) values of patients with cancer indicate that physical exercise should be implemented in their standard care.
Charlotte N Steins Bisschop; Miranda J Velthuis; Harriët Wittink; Kees Kuiper; Tim Takken; Wout J T M van der Meulen; Eline Lindeman; Petra H M Peeters; Anne M May
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Sports medicine (Auckland, N.Z.)     Volume:  42     ISSN:  1179-2035     ISO Abbreviation:  Sports Med     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-19     Completed Date:  2012-08-21     Revised Date:  2013-05-16    
Medline Journal Info:
Nlm Unique ID:  8412297     Medline TA:  Sports Med     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  367-79     Citation Subset:  IM    
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
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MeSH Terms
Exercise Test / methods*
Exercise Tolerance*
Feasibility Studies
Neoplasms / rehabilitation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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