| Cardiopulmonary Exercise Testing and SF-36 In Patients With Atrial Septal Defect Type Secundum. | |
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MedLine Citation:
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PMID: 21705914 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE:: Although exercise capacity is impaired, atrial septal defect (ASD) patients report satisfactory exercise tolerance. This study aimed at (1) evaluating cardiopulmonary exercise testing (CPX) and (2) evaluating the impact of exercise capacity on perceived health status using a self-reported health questionnaire (SF-36) in patients with open and closed ASD. METHODS:: Seventeen patients (mean age 37 ± 17, 9 males) with open ASD and 24 (mean age 37 ± 14, 6 male) with closed ASD were included. All underwent CPX and completed a SF-36 questionnaire. Age- and gender-matched controls were selected for comparison of CPX variables and SF-36 was compared with results from a general population. RESULTS:: Patients with open ASD had lower peak oxygen uptake (V[Combining Dot Above]O2) (27.9 ± 9.7 vs 38.5 ± 9.5 mL · kg · min. P = .009) and higher V[Combining Dot Above]E/V[Combining Dot Above]CO2 slope (31.0 ± 7.7 vs 24.1 ± 4.8; P = .004) than controls. Patients with closed ASD had lower peak V[Combining Dot Above]O2 (26.2 ± 8.4 vs 34.8 ± 9.7 mL · kg · min. P = .014) and peak heart rate (163 ± 25 vs 178 ± 16 bpm; P = .035) than controls. Perceived health-status was lower in patients with open ASD than the general population. Peak V[Combining Dot Above]O2 correlated significantly with physical functioning, emotional functioning, and bodily pain in open ASD and with physical functioning, bodily pain, role limitation, vitality, and mental health in closed ASD patients. CONCLUSION:: Patients with open and closed ASD had decreased peak V[Combining Dot Above]O2. Patients with open ASD had lower ventilatory efficiency. Closed ASD patients had chronotropic incompetence because of β-blockers. SF-36 was reduced in patients with open ASD but not closed ASD. Reduced exercise capacity affected several domains of perceived health-status in ASD patients. |
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Authors:
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Alexander Van De Bruaene; Roselien Buys; Luc Vanhees; Marion Delcroix; Philip Moons; Werner Budts |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-6-23 |
Journal Detail:
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Title: Journal of cardiopulmonary rehabilitation and prevention Volume: - ISSN: 1932-751X ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-6-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101291247 Medline TA: J Cardiopulm Rehabil Prev Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Structural and Congenital Cardiology (Drs Van De Bruaene and Budts), Department of Rehabilitation Sciences (Drs Buys and Vanhees), Department of Pneumology (Dr Delcroix), Centre for Health Services and Nursing Research, Division of Congenital and Structural Cardiology (Dr Moons); University Hospitals Leuven, Belgium. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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