Document Detail

Cardioprotective effect of mangiferin on isoproterenol induced myocardial infarction in rats.
MedLine Citation:
PMID:  16538859     Owner:  NLM     Status:  MEDLINE    
Isoproterenol (ISPH) induced myocardial infarction was confirmed by disturbances in serum and heart tissue marker enzymes such as lactate dehydrogenase (LDH), creatine phospho kinase (CPK), aspartate transaminase (AST) and alanine transaminase (ALT), increased level of lipid peroxidation and histopathological changes in the heart of ISPH administered rats. Pretreatment with mangiferin (10 mg/100 g body weight) for 28 days was found to ameliorate the effect of ISPH-induced pathological changes, reduced the lipid peroxide formation and retained the myocardial marker enzyme activities at near normal level. The above results indicate the cardioprotective effect of mangiferin against ISPH-induced myocardial infarction in rats.
S Prabhu; Mallika Jainu; K E Sabitha; C S Shyamala Devi
Related Documents :
3715799 - The co-operative action of hyaluronidase and urokinase on the isoproterenol-induced myo...
4089799 - White blood cell count and haematocrit as predictors of coronary recurrence after myoca...
3252969 - Myosin light chains release in acute myocardial infarction: non-invasive estimation of ...
2103899 - Quantitation of cumulative release of lactate dehydrogenase isoenzyme-1 in plasma of pa...
19251259 - C-reactive protein predicts functional status and correlates with left ventricular ejec...
1191429 - Serum cpk isoenzymes after cardiac catheterization.
10709829 - Myocardial inflammatory cell infiltrates in cases of dilated cardiomyopathy: light micr...
1638559 - A modified model of global ischaemia: application to the study of syncytial mechanisms ...
568399 - Acetate fails to reverse myocardial depression in dogs anesthetized with halothane.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of experimental biology     Volume:  44     ISSN:  0019-5189     ISO Abbreviation:  Indian J. Exp. Biol.     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-03-16     Completed Date:  2006-08-21     Revised Date:  2013-01-28    
Medline Journal Info:
Nlm Unique ID:  0233411     Medline TA:  Indian J Exp Biol     Country:  India    
Other Details:
Languages:  eng     Pagination:  209-15     Citation Subset:  IM    
Department of Biochemistry, University of Madras, Guindy Campus Chennai 600 025, India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Alanine Transaminase / metabolism
Aspartate Aminotransferases / metabolism
Cardiotonic Agents / pharmacology*
Dose-Response Relationship, Drug
Isoproterenol / pharmacology*
Myocardial Infarction / chemically induced*,  metabolism,  pathology,  prevention & control*
Rats, Wistar
Xanthones / pharmacology*
Reg. No./Substance:
0/Cardiotonic Agents; 0/Xanthones; 1M84LD0UMD/mangiferin; 7683-59-2/Isoproterenol; EC Aminotransferases; EC Transaminase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Induction and evaluation of atherosclerosis in New Zealand white rabbits.
Next Document:  Inhibitory effect of cinnamoyl compounds against human malignant cell line.