Document Detail


Cardioprotection by ischemic postconditioning during surgical procedures.
MedLine Citation:
PMID:  18666850     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute myocardial ischemic insult remains the most prevalent cause of postoperative mortality and morbidity despite major advances in cardiovascular medicine. Preoperative cardiac assessment and optimization, intraoperative anesthetic techniques and perioperative medical prophylaxis are all used to minimize cardiac morbidity. Ischemic postconditioning is one of the latest techniques to be added to this regime of cardioprotection. Currently still in its infancy, this technique seems to provide valuable cardioprotection via a novel set of pathways. We present a literature review of published animal and human studies on ischemic postconditioning, focusing on the advances made in understanding this phenomenon since its inception and the relevant clinical applications.
Authors:
Umar Sadat; Stewart R Walsh; Kevin Varty
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Expert review of cardiovascular therapy     Volume:  6     ISSN:  1744-8344     ISO Abbreviation:  Expert Rev Cardiovasc Ther     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-31     Completed Date:  2008-09-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101182328     Medline TA:  Expert Rev Cardiovasc Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  999-1006     Citation Subset:  IM    
Affiliation:
Clinical Research Associate Vascular Imaging, Cambridge Vascular Unit, Box 201, Department of Surgery, Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK. sadat.umar@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Arrhythmias, Cardiac / prevention & control
Cardiac Surgical Procedures / adverse effects*
Clinical Trials as Topic
Humans
Ischemic Preconditioning, Myocardial / methods*
Myocardial Ischemia / etiology,  prevention & control
Postoperative Complications / prevention & control*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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