| "Cardioneuroablation"--new treatment for neurocardiogenic syncope, functional AV block and sinus dysfunction using catheter RF-ablation. | |
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MedLine Citation:
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PMID: 15670960 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiac neuroablation is a new technique for management of patients with dominantly adverse parasympathetic autonomic influence. The technique is based on radiofrequency (RF) ablation of autonomic connections in the three main ganglia around the heart. Their connections are identified by Fast-Fourier Transforms (FFTs) of endocardial signals: sites of autonomic nervous connections show fractionated signals with FFTs shifted to the right. In contrast, normal myocardium without these connections does not show these features. RF-ablation is thought to inflict permanent damage on the parasympathetic autonomic influence because its cells are adjacent to the heart whereas sympathetic cells are remote. Twenty-one patients with a mean age of 48 years, neurally mediated reflex syncope in six, functional high grade atrioventricular block in seven and sinus node dysfunction in 13 (there is overlap between the second and third groups) were treated. Follow-up for a mean of 9.2 months demonstrated success in all cases with relief of symptoms. No complications occurred. |
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Authors:
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Jose C Pachon; Enrique I Pachon; Juan C Pachon; Tasso J Lobo; Maria Z Pachon; Remy N A Vargas; Adib D Jatene |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Volume: 7 ISSN: 1099-5129 ISO Abbreviation: Europace Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-01-26 Completed Date: 2005-06-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883649 Medline TA: Europace Country: England |
Other Details:
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Languages: eng Pagination: 1-13 Citation Subset: IM |
Affiliation:
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Sao Paulo Heart Hospital and Dante Pazzanese Cardiology Institute, Pacemaker and Arrhythmias, Acoce, 515/31 Indianopolis, 04075023 Sao Paulo, SP, Brazil. jcpachon@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Bradycardia / complications, physiopathology, surgery* Catheter Ablation / methods* Female Heart Block / etiology, physiopathology, surgery Heart Conduction System / physiopathology, surgery* Humans Male Middle Aged Signal Processing, Computer-Assisted Syncope, Vasovagal / etiology, physiopathology, surgery Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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