Document Detail


THE CARDIOMYOPATHY OF MUSCULAR DYSTROPHY: REPORT OF TWO CASES WITH A REVIEW OF THE LITERATURE.
MedLine Citation:
PMID:  14133625     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
About 50% of patients with progressive muscular dystrophy have a cardiomyopathy, manifested commonly by tachycardia, but also by arrythmias, refractory congestive heart failure and sudden death. Studies from the literature report manifold but nonspecific electrocardiographic changes in 41% to 85% of patients with progressive muscular dystrophy. The principal lesion is a diffuse myocardial fibrosis with minor degenerative changes in myocardial fibres unaccompanied by significant inflammation. The heart is enlarged and has a prominent deposit of epicardial fat. The myocardium is pale, coarse, flabby and friable, often showing gross evidence of scarring. The dilated chambers often contain mural thrombus.
Authors:
M A HOOEY; L M JERRY
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  90     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1964 Mar 
Date Detail:
Created Date:  1964-08-01     Completed Date:  1996-12-01     Revised Date:  2010-06-22    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  771-4     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Arrhythmias, Cardiac*
Cardiomegaly*
Electrocardiography*
Endocardium*
Heart Diseases*
Heart Failure*
Heart Septal Defects*
Muscular Dystrophies*
Myocardium*
Pathology*
Tachycardia*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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