| Cardiogenic shock without flow-limiting angiographic coronary artery disease: (from the Should We Emergently Revascularize Occluded Coronary Arteries for Cardiogenic Shock Trial and Registry). | |
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MedLine Citation:
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PMID: 19576316 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Myocardial infarction often develops when thrombosis occurs at lesions that have not previously been flow limiting. However, the development of cardiogenic shock complicating acute myocardial infarction in such circumstances has received little attention. The characteristics of 15 patients with cardiogenic shock who had no flow-limiting angiographic stenoses were compared with those of 767 patients with > or =1 stenosis who were enrolled in the Should We Emergently Revascularize Occluded Coronary Arteries for Cardiogenic Shock (SHOCK) trial and registry. Compared with patients with > or =1 flow-limiting stenosis, patients with no flow-limiting stenoses were less likely to have pulmonary edema on chest x-ray (29% vs 62%, p = 0.008) and to be white (53% vs 82%, p = 0.011), and they had lower median highest creatine kinase levels (702 vs 2,731 U/L, p = 0.018). For SHOCK trial patients, 1-year survival was 49% for patients with > or =1 flow-limiting stenosis and 71% for those with no flow-limiting stenoses (p = 0.268). In conclusion, patients with cardiogenic shock without flow-limiting stenosis have different characteristics, and potentially disease mechanisms, and they do not require revascularization. |
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Authors:
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John K French; Shannon Harkness; Lynn Sleeper; S Chiu Wong; Jacques Col; Vladimir Dzavik; Harvey D White; Judith S Hochman |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Randomized Controlled Trial Date: 2009-05-04 |
Journal Detail:
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Title: The American journal of cardiology Volume: 104 ISSN: 1879-1913 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-07-06 Completed Date: 2009-07-24 Revised Date: 2011-05-05 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 24-8 Citation Subset: AIM; IM |
Affiliation:
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Cardiology Department and South West Sydney Clinical School, University of New South Wales, Liverpool Hospital, Sydney, Australia. j.french@unsw.edu.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Coronary Angiography* Coronary Stenosis / complications, mortality, therapy* Coronary Vessels / pathology* Female Humans Male Middle Aged Myocardial Infarction / complications*, mortality, therapy Registries Risk Factors Shock, Cardiogenic / etiology, mortality, therapy* Ventricular Function, Left |
| Grant Support | |
ID/Acronym/Agency:
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R01 HL050020-05/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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