Document Detail


Cardiogenic shock with stunned myocardium during triple-H therapy treated with intra-aortic balloon pump counterpulsation.
MedLine Citation:
PMID:  18810666     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Excessive use of adrenergic agents may result in stunned myocardium. CASES: We report the cases of two patients with subarachnoid hemorrhage (SAH) complicated by cardiogenic shock secondary to triple-H therapy for cerebral vasospasm. Both patients had normal cardiac function on admission and no signs of acute myocardial infarction at the onset of cardiogenic shock. Intra-aortic balloon pump (IABP) counterpulsation was used to maintain adequate cerebral perfusion while enabling the high doses of norepinephrine that were being administered to be reduced. Reversal of the myocardial dysfunction after vasopressors were discontinued supported a diagnosis of catecholamine-induced stunned myocardium. CONCLUSION: IABP counterpulsation may be one therapeutic option for patients with vasospasm after SAH when high doses of vasopressors can induce severe myocardial dysfunction. However, this invasive device may not be sufficient to maintain adequate cerebral perfusion and fatal embolic events can complicate the clinical course.
Authors:
Fabio Silvio Taccone; Boris Lubicz; Michael Piagnerelli; Marc Van Nuffelen; Jean-Louis Vincent; Daniel De Backer
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-09-23
Journal Detail:
Title:  Neurocritical care     Volume:  10     ISSN:  1541-6933     ISO Abbreviation:  Neurocrit Care     Publication Date:  2009  
Date Detail:
Created Date:  2009-01-21     Completed Date:  2009-03-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101156086     Medline TA:  Neurocrit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  76-82     Citation Subset:  IM    
Affiliation:
Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, 808, 1070, Brussels, Belgium. ftaccone@ulb.ac.be
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Intra-Aortic Balloon Pumping*
Middle Aged
Myocardial Stunning / chemically induced,  diagnosis,  therapy*
Norepinephrine / adverse effects*
Shock, Cardiogenic / chemically induced,  diagnosis,  therapy*
Subarachnoid Hemorrhage / complications,  therapy
Vasoconstrictor Agents / adverse effects*
Vasospasm, Intracranial / etiology,  therapy
Chemical
Reg. No./Substance:
0/Vasoconstrictor Agents; 51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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