Document Detail


Cardiogenic shock in a neonate with enterovirus myocarditis.
MedLine Citation:
PMID:  20013569     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Left ventricular compromise in the neonate may be caused by birth asphyxia, metabolic disease, congenital heart disease, and systemic bacterial or viral infections. In rare cases, enterovirus infection may cause severe disease including cardiac, cerebral, hepatic and multi organ failure. PATIENTS AND METHODS: Case report. RESULTS: A 3-week-old neonate was admitted to our NICU in cardiogenic shock and severe lactic acidosis (ph: 6.9; serum lactate: 15 mmol/l, base excess: -19.8 mmol/l; pCO (2): 54.9 mm Hg). Serum troponin T was within the normal range; serum total creatinin phosphokinase was 57 U/l, CK-MB 110 U/l, LDH 762 U/l; pro-BNP: 64391 pg/ml was elevated. On echocardiography left ventricular function was depressed with a shortening fraction of 16%. The neonate was started on inotropes. There was gradual improvement over the following two weeks with normalisation of left ventricular output. PCR examination was positive for enterovirus. Other causes for left ventricular compromise (congenital heart disease, inborn errors of metabolism, etc.) were ruled out by adequate means. CONCLUSIONS: Enterovirus infection as a cause for myocarditis and cardiogenic shock should be taken into the differential diagnosis in neonates.
Authors:
S Meyer; L Gortner; S Gottschling; B G?rtner; H Abdul-Khaliq
Related Documents :
791649 - Heart failure in experimental refractory shock.
12475849 - Clinical features and outcome of patients with direct percutaneous coronary interventio...
20923829 - Remote muscle salvage by regional substrate enhancement during on-bypass beating-heart ...
2928649 - Direct effects of purified staphylococcal toxic shock syndrome toxin 1 on myocardial fu...
19468019 - Intractable cardiogenic shock in stress cardiomyopathy with left ventricular outflow tr...
2026029 - Oxygen consumption in sepsis and septic shock.
11523619 - Lead configuration for defibrillator implantation in a patient with congenital heart di...
22409689 - Appropriate indications for computed tomography coronary angiography.
9506609 - Alterations of neuropsychological function and cerebral glucose metabolism after cardia...
Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  Klinische P?diatrie     Volume:  221     ISSN:  1439-3824     ISO Abbreviation:  Klin Padiatr     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-16     Completed Date:  2010-03-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0326144     Medline TA:  Klin Padiatr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  444-7     Citation Subset:  IM    
Copyright Information:
(c) Georg Thieme Verlag KG Stuttgart New York.
Affiliation:
Department of Neonatology and Pediatric Intensive Care Medicine, University Hospital of Saarland, Homburg, Germany. sascha.meyer@unikliniksaarland.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Angiography
Bacteremia / diagnosis
Diagnosis, Differential
Echocardiography
Echocardiography, Doppler
Enterovirus Infections / diagnosis*,  transmission
Female
Humans
Infant, Newborn
Infectious Disease Transmission, Vertical
Intensive Care Units, Neonatal
Mitral Valve Insufficiency / diagnosis
Myocarditis / diagnosis*
Polymerase Chain Reaction
Pregnancy
Pregnancy Complications, Infectious / diagnosis
Shock, Cardiogenic / diagnosis*,  etiology*
Ventricular Dysfunction, Left / diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Primary ciliary dyskinesia causing neonatal respiratory distress
Next Document:  Developmental screening of preterms at an early stage postpartum