Document Detail

Cardiogenic shock in acute coronary syndrome in the Spanish population.
MedLine Citation:
PMID:  18971881     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To evaluate the frequency and factors associated with cardiogenic shock (CS) in acute myocardial infarction (AMI) and unstable angina (UA) and percutaneous coronary intervention (PCI). MATERIAL/METHODS: Spanish registry. The study period was June 1996 to December 2005. Follow-up was length of stay in an intensive care or coronary care unit (ICU/CCU). Multivariate studies evaluated factors associated with CS, mortality in CS, and PCI performance. RESULTS: The study included 45.688 AMI patients and 17.277 UA patients. Cardiogenic shock occurred in 9.3% of patients with AMI and 1.79% of those with UA, frequencies that decreased over time. Variables associated with cardiogenic shock in AMI patients were female sex, age, type of infarction, diabetes, previous stroke, arrhythmia, previous angiography, complicated angina, and reinfarction. Hypertension and oral beta-blocking, ACE inhibitor, and hypolipidemic agents protected against CS. In UA, these variables were age, previous angina or AMI, right ventricular heart failure, arrhythmia. Beta-blocking agents were associated with a reduction in CS. Deaths from CS and AMI, respectively, were 62.8% and 38.7% in persons with UA. Doing PCIs has increased significantly; it is more prevalent in ex-smokers and those with right ventricular heart failure and mechanical ventilation; lower performance is associated with need for cardiopulmonary resuscitation; patients who die are older or have a history of AMI. CONCLUSIONS: There has been a slight drop in the frequency of CS and its mortality. Factors associated with CS are similar to those associated with acute coronary syndromes. The frequency of PCI was low.
Manuel Ruiz Bailén; Luis Rucabado-Aguilar; Ana María Castillo-Rivera; Manuela Expósito-Ruiz; Antonia Morante-Valle; Juan José Rodríguez-García; Antonio Pintor-Mármol; Silvia Galindo-Rodríguez; María Isabel Ruiz-García; Francisco Javier Gómez Jiménez; Juan Carlos Fernández-Guerrero; Rafael Vázquez-García; Juan Angel Herrador Fuentes
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical science monitor : international medical journal of experimental and clinical research     Volume:  14     ISSN:  1643-3750     ISO Abbreviation:  Med. Sci. Monit.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-10-30     Completed Date:  2008-12-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9609063     Medline TA:  Med Sci Monit     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  PH46-57     Citation Subset:  IM    
Corory Cardiac Unit, Intensive Care Unit, Critical Care and Emergency Department, Medical-Surgical University Hospital, Jaen Hospital Complex, Jaen, Spain.
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MeSH Terms
Acute Coronary Syndrome / complications*,  epidemiology*,  surgery
Age Distribution
Aged, 80 and over
Catheter Ablation
Middle Aged
Shock, Cardiogenic / complications*,  epidemiology*,  surgery
Spain / epidemiology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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