Document Detail


Cardiogenic shock due to thrombotic thrombocytopenic purpura.
MedLine Citation:
PMID:  15252743     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the case of a 49-year-old man with thrombotic thrombocytopenic purpura (TTP) leading to cardiogenic shock. Laboratory data were typical for TTP with thrombocytopenia and microangiopathic hemolytic anemia. The electrocardiogram recorded significant ST-segment elevations in the anterior and inferior leads. In addition' coronary angiography showed normal epicardial coronary arteries with slow flow. The patient died due to electromechanical dissociation six hours after admission. During autopsy typical features of thrombotic thrombocytopenic purpura were found. Histological preparation of the heart showed a diffuse myocardial necrosis due to microvascular thrombosis. Cardiac involvement is common in TTP but extended myocardial necrosis has been reported in only a few cases.
Authors:
H Lapp; D-I Shin; W Kroells; G Boerrigter; M Horlitz; P Schley; S Stoerkel; H Guelker
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Zeitschrift für Kardiologie     Volume:  93     ISSN:  0300-5860     ISO Abbreviation:  Z Kardiol     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-07-14     Completed Date:  2004-09-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0360430     Medline TA:  Z Kardiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  486-92     Citation Subset:  IM    
Affiliation:
HELIOS Klinikum Wuppertal, Universität Witten/Herdecke Kardiologie, Medizinische Klinik 3, Arrenberger Str. 20, 42117 Wuppertal, Germany. hlapp@wuppertal.helios-kliniken.de
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MeSH Terms
Descriptor/Qualifier:
Diagnosis, Differential
Electrocardiography
Humans
Male
Middle Aged
Purpura, Thrombotic Thrombocytopenic / complications*,  diagnosis*,  pathology
Shock, Cardiogenic / diagnosis*,  etiology*,  pathology

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