Document Detail

Cardiogenic shock complicating acute coronary syndromes.
MedLine Citation:
PMID:  11085707     Owner:  NLM     Status:  MEDLINE    
Cardiogenic shock remains the major cause of death among patients with all types of acute coronary syndromes. Thus, there is a growing interest in the identification of patients who are at risk for developing cardiogenic shock, in the exploration of different therapeutic approaches to preventing its development, and in the improvement of outcome when it occurs. This article reviews the aetiology and pathophysiology of cardiogenic shock, its epidemiology, its treatment (including pharmaceutical agents, counterpulsation, and revascularisation), and its outcome. Algorithms are presented that predict its occurrence in both ST-segment-elevation myocardial infarction and unstable angina or non-ST-elevation myocardial infarction, and that predict its mortality in patients with ST-segment-elevation acute myocardial infarction. Such new areas as metabolic therapy and glycoprotein IIb/IIIa inhibitors are discussed, as are the economic implications of shock.
D Hasdai; E J Topol; R M Califf; P B Berger; D R Holmes
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Lancet     Volume:  356     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-11-30     Completed Date:  2000-11-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  749-56     Citation Subset:  AIM; IM    
Rabin Medical Center, Petah Tikva, Israel.
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MeSH Terms
Acute Disease
Aged, 80 and over
Coronary Disease / complications
Fibrinolytic Agents / therapeutic use
Middle Aged
Predictive Value of Tests
Randomized Controlled Trials as Topic
Risk Factors
Shock, Cardiogenic* / complications,  etiology,  physiopathology,  therapy
Reg. No./Substance:
0/Fibrinolytic Agents
Comment In:
Lancet. 2000 Nov 11;356(9242):1687-8   [PMID:  11089851 ]
Lancet. 2000 Nov 11;356(9242):1687   [PMID:  11089850 ]

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