Document Detail

Cardiogenic shock complicating acute carbon monoxide poisoning despite neurologic and metabolic recovery.
MedLine Citation:
PMID:  12239499     Owner:  NLM     Status:  MEDLINE    
We report the cases of 2 previously healthy young patients with acute carbon monoxide intoxication who deteriorated to cardiogenic shock in the face of apparent metabolic and neurologic recovery. Prolonged exposure to sublethal levels of carbon monoxide (>24 hours, carboxyhemoglobin level of 20.4% and 22.6%) and massive binding of the toxin to myocardial myoglobin and mitochondrial cytochrome chain enzymes might explain their protracted cardiac failure. The good response to inotropic agents and the findings of repeated echocardiographic studies support the probable diagnosis of myocardial stunning. Complete cardiac recovery was observed in both patients.
Yoav Yanir; Avi Shupak; Amir Abramovich; Shimon A Reisner; Abraham Lorber
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of emergency medicine     Volume:  40     ISSN:  0196-0644     ISO Abbreviation:  Ann Emerg Med     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-09-19     Completed Date:  2002-10-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  420-4     Citation Subset:  AIM; IM    
Israel Naval Medical Institute, IDF Medical Corps, Haifa.
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MeSH Terms
Carbon Monoxide Poisoning / complications*,  physiopathology,  therapy
Child, Preschool
Hyperbaric Oxygenation
Shock, Cardiogenic / etiology*,  physiopathology

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