Document Detail

Cardioembolic stroke revealed by increased hemostatic markers associated with intracardiac thrombus.
MedLine Citation:
PMID:  1926245     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: The presence of hemocoagulative disorders in acute ischemic stroke has been reported occasionally. However, the cause of the hemostatic derangement has not been fully elucidated. CASE DESCRIPTION: A 66-year-old woman with a history of hypertension and myocardial infarction developed pure motor hemiparesis. On admission, she was thought to have a lacunar infarction. However, computed tomography of the brain with contrast medium revealed a small infarct in the cortex of the frontal lobe. Conventional angiography showed no stenotic or occlusive lesions. Sensitive hemocoagulative tests revealed hypercoagulative and hyperfibrinolytic states. Ultrafast computed tomography of the heart with contrast enhancement demonstrated a large left ventricular mural thrombus. There were no further abnormal findings suggestive of other systemic diseases that affect blood coagulability. As a result, the patient was diagnosed as having suffered a cardioembolic stroke. CONCLUSIONS: An intracardiac thrombus could be one of the causes of the hemostatic disorders of acute cardioembolic stroke.
M Yasaka; T Yamaguchi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  22     ISSN:  0039-2499     ISO Abbreviation:  Stroke     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1991-11-18     Completed Date:  1991-11-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1317-9     Citation Subset:  IM    
Department of Medicine, National Cardiovascular Center, Osaka, Japan.
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MeSH Terms
Brain / radiography
Cerebral Angiography
Cerebrovascular Disorders / etiology*,  pathology,  physiopathology
Hemostasis / physiology*
Hypertension / physiopathology
Intracranial Embolism and Thrombosis / complications*,  pathology,  physiopathology
Myocardial Infarction / pathology,  physiopathology
Tomography, X-Ray Computed

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