Document Detail

Cardioembolic sources in stroke patients in South of Brazil.
MedLine Citation:
PMID:  25349734     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Background. Stroke is a leading cause of mortality and disability in Brazil and around the world. Cardioembolism is responsible for nearly 30% of the origins of ischemic stroke. Methods. We analyzed data of 256 patients with cardioembolic ischemic stroke (according to TOAST classification) who were admitted into the Hospital São Lucas-PUCRS from October 2011 to January 2014. The cardioembolic subtype was divided into six subgroups: arrhythmias, valvular heart disease, coronary artery disease, cardiomyopathy, septal abnormalities, and intracardiac injuries. The prevalence of the most important cardiovascular risk factors and medications in use for prevention of systemic embolism by the time of hospital admission was analyzed in each patient. Results. Among 256 patients aged 60.2 +/- 6.9 years, 132 males, arrhythmias were the most common cause of cardioembolism corresponding to 50.7%, followed by valvular heart disease (17.5%) and coronary artery disease (16%). Hypertension (61.7%) and dyslipidemia (43.7%) were the most common risk factors. Less than 50% of patients with arrhythmias were using oral anticoagulants. Conclusions. Identifying the prevalence of cardioembolic stroke sources subgroups has become an increasingly important role since the introduction of new oral anticoagulants. In this study, arrhythmias (especially atrial fibrillation) were the main cause of cardioembolism.
Luiz Carlos Porcello Marrone; João Pedro Farina Brunelli; Ricardo Lutzky Saute; Gustavo Henrique Tomasi; Bianca Cecchele Madeira; William Alves Martins; Robson Dupont Rohr; Ana Paula Heck; Luiz Ricardo Botton; Marilia Martins de Castro; Rodrigo Bodanese; Luiz Carlos Bodanese; Antônio Carlos Huf Marrone; Jaderson Costa da Costa
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Publication Detail:
Type:  Journal Article     Date:  2014-10-02
Journal Detail:
Title:  Thrombosis     Volume:  2014     ISSN:  2090-1488     ISO Abbreviation:  Thrombosis     Publication Date:  2014  
Date Detail:
Created Date:  2014-10-28     Completed Date:  2014-10-28     Revised Date:  2014-10-30    
Medline Journal Info:
Nlm Unique ID:  101566937     Medline TA:  Thrombosis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  753780     Citation Subset:  -    
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