Document Detail

Cardiodynamic factors affecting hyperpnea during steady-state exercise in man.
MedLine Citation:
PMID:  2507814     Owner:  NLM     Status:  MEDLINE    
In order to know the role of cardiodynamic factors for exercise hyperpnea, ventilation and several cardiorespiratory variables were measured simultaneously in human subjects during exercise. Cardiac output (Q) and mixed venous CO2 content (CVCO2) were determined by a rebreathing method. The correlation coefficients (r) for the relationships between minute expiratory ventilation (VE) and each of end-tidal CO2 tension (PETCO2), Q, CVCO2, CO2 flow into the lung (QCO2, the product of Q and CVCO2), oxygen consumption (VO2), and CO2 output (VCO2) were determined during the steady-state exercise up to 90 W. The correlation was highly significant (r = 0.84-0.99, p less than 0.001) in each case except for PETCO2 (r = 0.13, N.S.). The highest correlation was observed in the VE-VCO2 relationship. It was assume that VCO2 released from the pulmonary capillaries into the alveoli is the most likely stimulus leading to exercise hyperpnea. Arterial CO2 oscillation may be regarded as a potential linkage between VCO2 and VE.
Y Miyamoto; K Niizeki; K Kawahara; K Doi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Japanese journal of physiology     Volume:  39     ISSN:  0021-521X     ISO Abbreviation:  Jpn. J. Physiol.     Publication Date:  1989  
Date Detail:
Created Date:  1989-11-07     Completed Date:  1989-11-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  2985184R     Medline TA:  Jpn J Physiol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  411-20     Citation Subset:  IM; S    
Department of Information Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Japan.
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MeSH Terms
Blood Gas Analysis
Carbon Dioxide / blood,  physiology*
Cardiac Output*
Exercise Test
Heart Rate
Oxygen / blood
Physical Exertion*
Pulmonary Gas Exchange
Respiratory Function Tests
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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