Document Detail

Cardio-ankle vascular index is a new noninvasive parameter of arterial stiffness.
MedLine Citation:
PMID:  17965489     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Beta is an index of arterial stiffness independent of blood pressure. Beta of the thoracic descending aorta (TDA) has been obtained by transesophageal echocardiography (TEE) and the cardio-ankle vascular index (CAVI) is a new noninvasive estimation of beta. METHODS AND RESULTS: The purpose of this study was to evaluate the accuracy and usefulness of CAVI and to compare it with other parameters of arteriosclerosis by carotid ultrasound (CU). The instantaneous dimensional change of the TDA on TEE was measured simultaneously with systemic pressure of the brachial artery in 70 patients in sinus rhythm. There were significant correlations between CAVI and age (r=0.65, p<0.01), and CAVI and the beta from TEE (Aobeta) (r=0.67, p<0.01). Next, 110 patients with chest pain syndrome underwent CU and measurement of CAVI, intima - media thickness (IMT), plaque score and beta. There were significant relationships between CAVI and IMT (r=0.42, p<0.01), and between CAVI and beta (r=0.39, p<0.01). CAVI of the group diagnosed with plaque was significant higher than that of the normal group (9.872+/-1.464 vs 9.038+/-1.377, p=0.0039). CONCLUSIONS: CAVI is measured easily and noninvasively and is a new index of arterial stiffness that is independent of blood pressure.
Akira Takaki; Hiroshi Ogawa; Takatoshi Wakeyama; Takahiro Iwami; Masayasu Kimura; Yasuyuki Hadano; Susumu Matsuda; Yousuke Miyazaki; Tomoko Matsuda; Atsushi Hiratsuka; Masunori Matsuzaki
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  71     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-10-29     Completed Date:  2008-02-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1710-4     Citation Subset:  IM    
Division of Cardiology, Tokuyama Central Hospital, Shunan, Japan.
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MeSH Terms
Aged, 80 and over
Ankle / blood supply
Aorta, Thoracic / physiopathology*,  ultrasonography*
Atherosclerosis / physiopathology*
Blood Pressure / physiology
Brachial Artery / physiopathology*,  ultrasonography*
Carotid Arteries / physiopathology*,  ultrasonography*
Cholesterol / blood
Cholesterol, HDL / blood
Cholesterol, LDL / blood
Echocardiography, Transesophageal
Middle Aged
Triglycerides / blood
Tunica Intima / pathology,  ultrasonography
Tunica Media / pathology,  ultrasonography
Ultrasonography, Interventional
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides; 57-88-5/Cholesterol

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