Document Detail

Cardiff puerperal mood and hormone study. 1. Saliva steroid hormone profiles in late pregnancy and the puerperium: endocrine factors and parturition.
MedLine Citation:
PMID:  8262475     Owner:  NLM     Status:  MEDLINE    
Participants were 120 primiparous women who had vaginal delivery of a non-handicapped child. Saliva was collected twice daily through parturition to day 35 post-partum. In the prepartum, a highly significant circadian rhythm was seen in cortisol, with a lower-amplitude rhythm in progesterone (AM/PM = 1.12). Evening samples showed a rise in cortisol, with a highly significant rise on day -1. The rise was small. The fall in progesterone in the 3 days before parturition was also small (approximately 6%). Neither change provides an obvious trigger for parturition.
B Harris; L Lovett; S Roberts; G F Read; D Riad-Fahmy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hormone research     Volume:  39     ISSN:  0301-0163     ISO Abbreviation:  Horm. Res.     Publication Date:  1993  
Date Detail:
Created Date:  1994-01-27     Completed Date:  1994-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0366126     Medline TA:  Horm Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  138-45     Citation Subset:  IM    
Department of Psychological Medicine, University Hospital of Wales, Cardiff, UK.
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MeSH Terms
Circadian Rhythm
Hydrocortisone / metabolism*
Labor, Obstetric / physiology*
Postpartum Period / physiology*
Progesterone / metabolism*
Saliva / metabolism*
Reg. No./Substance:
50-23-7/Hydrocortisone; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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