| Cardiac tumors and the nevoid basal cell carcinoma syndrome. | |
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MedLine Citation:
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PMID: 2020522 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nevoid basal cell carcinoma syndrome is a multisystem disease with a wide range of initial symptoms that can be seen at any age. The most characteristic features are vertebral or rib anomalies, intracranial falx calcification, multiple basal cell carcinomas, odontogenic keratocysts of the jaw, and palmar and/or plantar pits. Pediatricians need to be aware that if any one of these major anomalies is seen, this diagnosis should be considered. There now appears to be an established association between cardiac tumors and nevoid basal cell carcinoma syndrome. Primary cardiac tumors have been associated with cerebral tuberous sclerosis and neurofibromatosis, and evaluation of cardiac status is recommended when these genetically determined syndromes are diagnosed. This communication should serve to alert pediatricians to the need for complete cardiac evaluation and genetic counseling when a diagnosis of nevoid basal cell carcinoma is made. |
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Authors:
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J L Cotton; R E Kavey; C E Palmier; W W Tunnessen |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatrics Volume: 87 ISSN: 0031-4005 ISO Abbreviation: Pediatrics Publication Date: 1991 May |
Date Detail:
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Created Date: 1991-05-29 Completed Date: 1991-05-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 725-8 Citation Subset: AIM; IM |
Affiliation:
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Dept. of Pediatrics, State University of New York, Syracuse. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Basal Cell Nevus Syndrome
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diagnosis* Child, Preschool Fibroma / diagnosis* Heart Neoplasms / diagnosis* Heart Ventricles Humans Male Neoplasms, Multiple Primary / diagnosis* Skin Neoplasms / diagnosis* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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