| Cardiac troponin I: a marker for post-burn cardiac injury. | |
| | |
MedLine Citation:
|
PMID: 10902859 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cardiac troponin I (cTnI) was measured by chemiluminescent immunoassay following burn injury. Thirty patients [total body surface area (TBSA) of burn 15-98%] were included in this study and each had four to six blood samples collected at 2-day intervals between the 5th and 14th days post-burn. All patients were found to have increased cTnI on two or more occasions. The mean cTnI concentration was significantly higher in patients with TBSA of burn > 30% (0.34 microg/L compared with 0.09 microg/L, P<0.001) and in those with obvious burn wound exudation (0.32 microg/L compared with 0.12 microg/L, P<0.01). cTnI concentrations peaked at the time when there was obvious burn wound exudation or spontaneous separation of eschar, then decreased after surgical excision. Two patients with persistently high cTnI concentrations developed tachycardia. We conclude that burned patients have varying degrees of non-ischaemic cardiac injury, manifesting as leakage of cTnI from myocytes into the circulation. |
| | |
Authors:
|
Y N Chen; Z R Luo; L J Zeng; M Y Wu; Y Z Wu; Z Y Lin |
Related Documents
:
|
21406999 - Single photon emission computed tomography striatal asymmetry index may predict dopamin... 19845149 - Overweight patients with severe sleep apnea experience deeper oxygen desaturation at ap... 17502699 - Red blood cell deformability in patients with sepsis: a marker for prognosis and monito... 11533009 - Effect of serum from different patient populations on the serum bactericidal test. 21585169 - Nephrolithiasis in medullary sponge kidney. 9201529 - Nitric oxide synthase inhibition by l-name in leukocytopenic patients with severe septi... 308889 - The role of the radiologist in acute gastrointestinal bleeding. 16324959 - Overuse of prothrombin and partial thromboplastin coagulation tests in medical inpatients. 8029429 - Distal ureteral calculi: detection with vaginal us. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Annals of clinical biochemistry Volume: 37 ( Pt 4) ISSN: 0004-5632 ISO Abbreviation: Ann. Clin. Biochem. Publication Date: 2000 Jul |
Date Detail:
|
Created Date: 2000-10-16 Completed Date: 2000-12-07 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0324055 Medline TA: Ann Clin Biochem Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 447-51 Citation Subset: IM |
Affiliation:
|
Department of Clinical Laboratory, Guang Zhou Red Cross Hospital, P R China. stsxns@zsulink.zsu.edu.cn |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Biological Markers* Burns* Cardiovascular Diseases / etiology Chemiluminescent Measurements Child Child, Preschool Female Humans Immunoassay Male Middle Aged Myocardium / metabolism* Tachycardia Time Factors Troponin I / blood* |
| Chemical | |
Reg. No./Substance:
|
0/Biological Markers; 0/Troponin I |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Evaluation of early response to SU101 target-based therapy in patients with recurrent supratentorial...
Next Document: Effects of bilirubin and its photoisomers on direct bilirubin measurement using bilirubin oxidase.