| Cardiac troponin I in pastured and race-training Thoroughbred horses. | |
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MedLine Citation:
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PMID: 12892316 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiac troponin I (cTnI), a myocardial polypeptide, is a highly sensitive and specific biomarker of myocardial injury in people and dogs. The structure of cTnI is highly conserved across species, and equine myocardium has high reactivity with human immunoassays. The purpose of this study was to describe cTnI concentrations in normal pastured and race-training Thoroughbred horses. Ten horses on pasture and 10 horses in race training were studied. Horses were considered normal on the basis of physical examination, training performance, electrocardiography (ECG), and echocardiography. Serum cTnI concentrations were determined with a colorimetric immunoassay. The assay has an analytical sensitivity of 0.04 ng/mL. Serum cTnI concentrations in race-training horses were not significantly different from those of pastured horses. When groups were combined, mean cTnI concentration (+/- SD) was 0.047 +/- 0.085 ng/mL. and the median was 0 (range, 0-0.35 ng/mL). The 90th percentile for both groups combined was 0.11 ng/mL. This study establishes a preliminary reference range for serum cTnI in normal Thoroughbred horses. |
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Authors:
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Wade Phillips; Steeve Giguère; Robert P Franklin; Jorge Hernandez; Darcy Adin; John G Peloso |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine Volume: 17 ISSN: 0891-6640 ISO Abbreviation: J. Vet. Intern. Med. Publication Date: 2003 Jul-Aug |
Date Detail:
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Created Date: 2003-08-01 Completed Date: 2003-09-12 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8708660 Medline TA: J Vet Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 597-9 Citation Subset: IM |
Affiliation:
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Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animal Husbandry Animals Breeding Female Horses / blood* Male Physical Conditioning, Animal* Physical Endurance Reference Values Running Troponin I / blood* |
| Chemical | |
Reg. No./Substance:
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0/Troponin I |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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