Document Detail

Cardiac troponin T in newborn infants with transient myocardial ischemia.
MedLine Citation:
PMID:  9535533     Owner:  NLM     Status:  MEDLINE    
Cardiac troponin T (TnT) is a regulatory contractile protein whose detection in the circulation has been shown to be a specific and sensitive marker for ischemic myocardial cell injury both in adult and pediatric populations. We measured serum cardiac TnT in 15 consecutive full-term neonates presenting with bradycardia and electrocardiographic features of transient myocardial ischemia. Their median TnT concentrations (0.5 microg/l, range 0.01-0.37) were statistically comparable to our laboratory reference values for healthy term newborns (median 0.17 microg/l, range 0.01-0.42) (p = NS), but significantly higher with respect to our reference limits for healthy adults (median 0.01 micog/l, range 0.01-0.1) (p < 0.05). Our data demonstrate high TnT levels in neonates during the first days of life with respect to adults and similar TnT concentrations in term infants with and without TMI.
D Trevisanuto; M Lachin; M Zaninotto; P A Pellegrino; M Plebani; F Cantarutti; V Zanardo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biology of the neonate     Volume:  73     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1998  
Date Detail:
Created Date:  1998-05-08     Completed Date:  1998-05-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  161-5     Citation Subset:  IM    
Pediatric Department, University of Padova, Italy.
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MeSH Terms
Infant, Newborn
Myocardial Ischemia / blood*,  diagnosis
Reference Values
Troponin / blood*
Troponin T
Reg. No./Substance:
0/Troponin; 0/Troponin T

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