| Cardiac tamponade and large pericardial effusions in systemic sclerosis : A report of four cases and a review of the literature. | |
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MedLine Citation:
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PMID: 21234631 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Cardiac tamponade in systemic sclerosis is rare. We report four cases of SSc with hemodynamically significant pericardial effusions associated with pulmonary arterial hypertension, three of whom died, two following pericardiocentesis. Of 26 SSc cases reported in the literature with large pericardial effusions, seven were associated with PAH. Including our series, the mortality rate is 55%.The potential contributory role of PAH in the development of pericardial effusion and the management implications are explored. In SSc patients with hemodynamically significant pericardial effusions and severe pulmonary hypertension, initial stabilization of pulmonary artery pressure and right heart function with vasoactive therapy and then cautious pericardial drainage should be considered. |
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Authors:
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James V Dunne; Julie P Chou; Mohan Viswanathan; Pearce Wilcox; Simon H Huang |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-1-14 |
Journal Detail:
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Title: Clinical rheumatology Volume: - ISSN: 1434-9949 ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-1-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211469 Medline TA: Clin Rheumatol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Medicine, St. Paul's Hospital and University of British Columbia, Vancouver, BC, Canada, James.Dunne@VCH.ca. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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