| Cardiac tamponade and cardiogenic shock as a manifestation of all-trans retinoic acid syndrome: an association not previously reported. | |
| | |
MedLine Citation:
|
PMID: 9299864 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Since the discovery of the differentiating activity of all-trans retinoic acid (ATRA) in acute promyelocytic leukemia (APL), the treatment of this disease has greatly improved. Currently, the combination of ATRA and chemotherapy is considered the best treatment for patients with APL. This approach has consistently extended the remission rate and disease-free survival of APL patients with low mortality. Among ATRA's adverse effects, the retinoic acid syndrome is the most important. It consists of fever, dyspnea, weight gain, pulmonary infiltrates and pleural and cardiac effusions. Other findings occasionally described are lower extremities edema and leukocytosis. We report a case of an retinoic acid syndrome associated with cardiac tamponade due to massive pericardial effusion. This adverse effect, not previously reported, was successfully treated by performing pericardiocentesis followed by the administration of dexamethasone. |
| | |
Authors:
|
L Larrea; J de la Rubia; C Jiménez; G Martín; M A Sanz |
Related Documents
:
|
1751134 - Determination of critical pericardial dimensions in patients with dilated cardiomyopathy. 10150624 - The paradoxical pulse in tamponade: mechanisms and echocardiographic correlates. 17543244 - Impedance cardiography: more questions than answers. 7736744 - Evaluation of a new continuous thermodilution cardiac output monitor in critically ill ... 20204434 - S100b: a multifunctional role in cardiovascular pathophysiology. 20634484 - Gene delivery of sarcoplasmic reticulum calcium atpase inhibits ventricular remodeling ... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Haematologica Volume: 82 ISSN: 0390-6078 ISO Abbreviation: Haematologica Publication Date: 1997 Jul-Aug |
Date Detail:
|
Created Date: 1997-10-06 Completed Date: 1997-10-06 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0417435 Medline TA: Haematologica Country: ITALY |
Other Details:
|
Languages: eng Pagination: 463-4 Citation Subset: IM |
Affiliation:
|
Servicio de Hematología, Hospital Universitario La Fe, Valencia, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cardiac Tamponade / etiology*, physiopathology, therapy Humans Leukemia, Promyelocytic, Acute / drug therapy* Male Shock, Cardiogenic / etiology*, physiopathology, therapy Tretinoin / adverse effects*, therapeutic use |
| Chemical | |
Reg. No./Substance:
|
302-79-4/Tretinoin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Long-lasting effect of cyclosporin-A on anemia associated with idiopathic myelofibrosis.
Next Document: Idiopathic myelofibrosis with neutrophil myeloperoxidase deficiency: a case report.