Document Detail

Cardiac surgery in type-1-myotonic muscular dystrophy (Steinert syndrome) associated to Barlow disease.
MedLine Citation:
PMID:  18208845     Owner:  NLM     Status:  MEDLINE    
No data exist in the English-language literature about patients with Barlow disease associated to Steinert syndrome and little is known about the employment of hypothermic cardiopulmonary bypass (CPB) and hyperkalemic cardioplegia in these patients. We present our experience with six patients affected by myxomatous degeneration associated to Steinert disease undergoing complex mitral valve repair. In all patients we employed mild hypothermic CPB (31 degrees C) and myocardial protection was achieved, in the entire cohort, by the use of blood hyperkalemic cold cardioplegia. The postoperative course was uneventful in all patients and neither shivering nor generalized muscle contraction were observed. Furthermore, all patients have remained well on an outpatient basis. Hypothermic CPB and hyperkalemic cardioplegia can be safely employed in patients with Steinert syndrome requiring complex cardiac surgery. Further large studies are necessary to confirm our findings.
Sandro Gelsomino; Roberto Lorusso; Giuseppe Billè; Giuseppe De Cicco; Ugo Da Broi; Carlo Rostagno; Pierluigi Stefàno; Gian Franco Gensini
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Publication Detail:
Type:  Journal Article     Date:  2008-01-21
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  7     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-04-02     Completed Date:  2008-05-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  222-6     Citation Subset:  IM    
Experimental Surgery Unit, Cardiac Surgery, Department of Heart and Vessels, Careggi Hospital, Viale Morgagni 85, 50134, Florence, Italy.
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MeSH Terms
Cardiac Surgical Procedures* / adverse effects
Cardiopulmonary Bypass* / adverse effects
Follow-Up Studies
Heart Arrest, Induced* / adverse effects,  methods
Hypothermia, Induced* / adverse effects
Middle Aged
Mitral Valve Prolapse / etiology,  surgery*
Myotonic Dystrophy / complications*,  surgery
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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