| Cardiac surgery and hypertension: a dangerous association that must be well known. | |
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MedLine Citation:
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PMID: 21894419 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is well-known that hypertension is a very common disease, and severe cerebrovascular accidents might occur if the blood pressure is not properly controlled. However, conditions associated with uncontrolled hypertension may be overlooked, and may become critical and eventually require a surgical intervention on an urgent basis. Coronary artery disease, acute aortic syndrome, congenital and valvular heart disease, and arrhythmias are under this topic of discussion. Of them, coronary artery disease including myocardial infarction and especially postinfarction myocardial rupture, and aortic dissection are major critical situations that physicians may encounter in clinical practice. The role that hypertension plays in these conditions can be complex, including hemodynamic, electrophysiological and biomolecular factors, where the latter may prevail in the current era. Coronary artery disease may be associated with a reduced nitric oxide synthesis. Transforming growth factor and matrix metalloproteinases have been observed in relation to aortic syndrome. Wnt, p38 and JNK signaling pathway may be involved in the development of ventricular hypertrophy responsible for cardiac arrythmias. Various gene phynotypes may present in different congenital heart defects. This article is to present these conditions, and to further discuss the possible etiologies and the potential treatment strategies so as to highlight the relevance at a prognostic level. |
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Authors:
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Shi-Min Yuan; Hua Jing |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular Volume: 26 ISSN: 1678-9741 ISO Abbreviation: Rev Bras Cir Cardiovasc Publication Date: 2011 Apr-Jun |
Date Detail:
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Created Date: 2011-09-06 Completed Date: 2012-04-19 Revised Date: 2012-10-31 |
Medline Journal Info:
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Nlm Unique ID: 9104279 Medline TA: Rev Bras Cir Cardiovasc Country: Brazil |
Other Details:
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Languages: eng Pagination: 273-81 Citation Subset: IM |
Affiliation:
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Department of Cardiothoracic Surgery, Affiliated Hospital of Taishan Medical College, Taian 27100,Shandong Province, People's Republic of China. shi_min_yuan@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aortic Diseases / etiology*, surgery Arrhythmias, Cardiac / etiology*, surgery Coronary Artery Disease / etiology*, surgery Heart Defects, Congenital / etiology*, surgery Humans Hypertension / complications* Syndrome |
| Comments/Corrections | |
Comment In:
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Rev Bras Cir Cardiovasc. 2012 Jan-Mar;27(1):173
[PMID:
22912995
]
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Erratum In:
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Rev Bras Cir Cardiovasc. 2012 Jan-Mar;27(1):173
[PMID:
22912995
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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