| Cardiac structure and function in normal pregnancy. | |
| | |
MedLine Citation:
|
PMID: 23000697 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
PURPOSE OF REVIEW: To review the published data on maternal cardiac adaptation to pregnancy. RECENT FINDINGS: Normal pregnancy is characterized by significant changes in the cardiovascular system. Studies on systemic arterial system and heart remodelling in pregnancy provide somewhat uniform results. In normal pregnancy, left ventricle mass, cardiac output and arterial compliance increase, whereas total vascular resistance decreases. In contrast, findings on left ventricular systolic and diastolic chamber and myocardial function are conflicting. SUMMARY: The major limitation of earlier studies on left ventricular systolic function is the use of ejection-phase indices that are dependent on loading conditions. Even when tissue Doppler velocity and deformation indices were measured, studies interpreted diastolic indices in isolation, rather than using validated diagnostic algorithms which account for the interdependency of cardiac events. Furthermore, the strong age-dependency of diastolic function indices was not accounted for in the majority of assessments and none of the studies diagnose or grade diastolic dysfunction. Future studies should aim to use appropriate control individuals, age-adjusted cutoff of cardiac diastolic indices and extended tissue Doppler velocity and deformation indices to provide objective information about chamber and myocardial function. |
| | |
Authors:
|
Karen Melchiorre; Rajan Sharma; Basky Thilaganathan |
Related Documents
:
|
19757257 - The rationale for the use of measles post-exposure prophylaxis in pregnant women: a rev... 6986087 - A prospective study of acquired toxoplasmosis among 8,043 pregnant women in the oslo area. 542317 - The effect of age, acquired resistance, pregnancy and lactation on some reactions of ca... 19632027 - Maternal and fetal consequences of dengue fever during pregnancy. 16726997 - Effects of breed, age of donor and dosage of follicle stimulating hormone on the supero... 16334847 - Fetal biometry: size and configuration of the third ventricle. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-9-20 |
Journal Detail:
|
Title: Current opinion in obstetrics & gynecology Volume: - ISSN: 1473-656X ISO Abbreviation: Curr. Opin. Obstet. Gynecol. Publication Date: 2012 Sep |
Date Detail:
|
Created Date: 2012-9-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9007264 Medline TA: Curr Opin Obstet Gynecol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
aFetal Maternal Medicine Unit, Department of Obstetrics and Gynecology, St George's Hospital, University of London, London, United Kingdom bDepartment of Obstetrics and Gynecology, Santo Spirito Hospital, Pescara, Italy cDepartment of Cardiology and Cardiothoracic Surgery, St George's Hospital, University of London, London, United Kingdom. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Prelabour rupture of membranes: overview of diagnostic methods.
Next Document: Gestational diabetes and childhood obesity: what is the link?