Document Detail

Cardiac rhabdomyomas and their association with tuberous sclerosis.
MedLine Citation:
PMID:  8466239     Owner:  NLM     Status:  MEDLINE    
A search for children presenting with signs or symptoms of cardiac rhabdomyomas was made through members of the paediatric section of the British Cardiac Society in order to establish their birth incidence, presenting features, clinical course, and the frequency of a concurrent diagnosis of tuberous sclerosis. Fifteen children were identified and 12 had tuberous sclerosis (80%). Heart failure was the presentation in six, five of whom died; six presented because of a murmur and three because of arrhythmias. The prevalence of echocardiographic evidence of cardiac rhabdomyomas in a population of patients with tuberous sclerosis was established. Twenty individuals had echocardiography and eight had echodensities consistent with cardiac rhabdomyomas. It is concluded that the minimum birth incidence for children presenting because of the effects of cardiac rhabdomyomas is 1/326,000 and a minimum of 80% have tuberous sclerosis. In a population of patients with tuberous sclerosis a minimum of 60% under 18 years have cardiac rhabdomyomas.
D W Webb; R D Thomas; J P Osborne
Related Documents :
16962479 - Post-mortem administration of urokinase in canine lung transplantation from non-heart-b...
16351989 - Prospective development of a cardiac surgical registry.
3399429 - Heart-rate spectral analysis: a noninvasive probe of cardiovascular regulation in criti...
11426479 - An exceptional case of complete neurologic recovery after more than 5-h cardiac arrest.
8752819 - Myocardial dysfunction after resuscitation from cardiac arrest: an example of global my...
17786379 - Sinus bradycardia, wolff parkinson white, and left ventricular noncompaction: an embryo...
1571989 - Coronary and left ventricular pacing as standby in invasive cardiology.
15865839 - Slow and wide qrs complex tachycardia as a unique complication following radiofrequency...
961589 - Intraventricular trifascicular block verified by his bundle electrocardiography.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  68     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-05-04     Completed Date:  1993-05-04     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  367-70     Citation Subset:  AIM; IM    
Bath Unit for Research into Paediatrics, Royal United Hospital, Combe Park.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Heart Neoplasms / complications*,  pathology
Infant, Newborn
Myocardium / pathology
Rhabdomyosarcoma / complications*,  pathology
Tuberous Sclerosis / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Treatment of severe steroid dependent preschool asthma with nebulised budesonide suspension.
Next Document:  Protein restriction in chronic renal failure.