| Cardiac resynchronization therapy in left ventricular hypertrabeculation/non-compaction and myopathy. | |
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MedLine Citation:
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PMID: 18029382 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: Little is known how patients with left ventricular hypertrabeculation/non-compaction (LVHT) and heart failure respond to cardiac resynchronization therapy (CRT). METHODS AND RESULTS: Included in this retrospective study were 8/102 patients (3 female, age range 43-78 years), in whom LVHT was diagnosed and in whom a CRT system was implanted. All eight patients were investigated neurologically and in seven of them a myopathy was found. The mean follow-up after CRT implantation was 39 (4-68) months. All patients improved by one or more New York Heart Association (NYHA) classes, and two by two NYHA classes. The left ventricular end-diastolic diameter decreased by < or =5% in 2 patients, by 6-10% in 3 patients, by 12% in 1 patient, and by >30% in 2 patients. The left ventricular systolic function, as assessed by the fractional shortening, did not change in 2 patients, increased by 10% in 2 patients, by 59% in 1 patient, doubled in 2 patients, and showed a five-fold increase in 1 patient. Two patients died during follow-up. CONCLUSION: CRT by biventricular pacing in LVHT, heart failure, and myopathy leads to improvement in functional capacity in all patients and improvement of systolic function in half of the patients. The weak response of LVHT patients to CRT may be due to inappropriate selection or comorbidities, in particular, neuromuscular disorders. |
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Authors:
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Claudia Stöllberger; Gerhard Blazek; Elisabeth Bucher; Josef Finsterer |
Publication Detail:
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Type: Journal Article Date: 2007-11-19 |
Journal Detail:
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Title: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Volume: 10 ISSN: 1532-2092 ISO Abbreviation: Europace Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2008-01-17 Completed Date: 2008-03-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883649 Medline TA: Europace Country: England |
Other Details:
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Languages: eng Pagination: 59-62 Citation Subset: IM |
Affiliation:
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2. Medizinische Abteilung, Krankenanstalt Rudolfstiftung, Juchgasse 25, 1030 Wien, Osterreich. claudia.stoellberger@chello.at |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Cardiac Pacing, Artificial / methods* Female Heart Failure / etiology, physiopathology, prevention & control Heart Ventricles / physiopathology Humans Male Middle Aged Neuromuscular Diseases / complications, physiopathology, therapy* Pacemaker, Artificial* Retrospective Studies Treatment Outcome Ventricular Dysfunction, Left / complications, physiopathology, therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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