| Cardiac resynchronization therapy: effects on left and right ventricular ejection fraction during exercise. | |
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MedLine Citation:
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PMID: 15683474 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In patients with heart failure and wide QRS complex, cardiac resynchronization therapy (CRT) is associated with improvement of symptoms and cardiac function. This study examined the effects of a 3-month period of CRT on left ventricular (LV) and right ventricular (RV) ejection fraction (EF) and on LV volumes, both at rest and during exercise. A CRT system was implanted in 15 patients with severe heart failure and wide QRS. Before implant and 3 months later, all patients underwent assessment of cardiac performance with equilibrium Tc(99) radionuclide angiography with imaging in the best septal left anterior oblique view. Exercise was performed on a bicycle ergometer. At 3 months, a significant improvement in New York Heart Association functional class was observed, and radionuclide angiography showed a significant decrease in LV volumes and a significant increase in LVEF at rest, as well as a significant increase in LVEF during exercise. The remodeling processes associated with CRT did not appear to include RV function, since RVEF did not improve, and changes in RVEF did not correlate with changes in LVEF, neither at rest nor during exercise. |
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Authors:
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Giuseppe Boriani; Francesco Fallani; Cristian Martignani; Mauro Biffi; Davide Saporito; Cristiano Greco; Matteo Ziacchi; Maurizio Levorato; Giulia Pontone; Cinzia Valzania; Igor Diemberger; Roberto Franchi; Angelo Branzi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 28 Suppl 1 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-02-01 Completed Date: 2005-06-03 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: S11-4 Citation Subset: IM |
Affiliation:
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Institute of Cardiology, University of Bologna. Bologna, Italy. cardio1@med.unibo.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiac Pacing, Artificial* Exercise Test Female Heart Failure / physiopathology*, radionuclide imaging, therapy* Humans Male Middle Aged Radionuclide Ventriculography Stroke Volume* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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