| Cardiac resynchronization therapy for the causal treatment of heart failure with preserved ejection fraction: insight from a pressure-volume loop analysis. | |
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MedLine Citation:
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PMID: 20436036 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This case describes a middle-aged patient with normal ejection fraction (64%) and significant dyspnoea which could not be explained by results from routine examinations. A pressure-volume loop analysis revealed severe left ventricular (LV) dyssynchrony to be the underlying mechanism of heart failure. The patient underwent implantation of a biventricular pacemaker. Cardiac resynchronization therapy (CRT) was associated with an immediate reduction in LV dyssynchrony from 32 to 13%, decrease in LV end-diastolic pressure from 19 to 8 mmHg, and increased exercise tolerance during follow-up. Thus, CRT may be considered a causal therapy in selected patients with heart failure and preserved ejection fraction. |
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Authors:
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Martin Penicka; Viktor Kocka; Dalibor Herman; Helena Trakalova; Martin Herold |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-04-30 |
Journal Detail:
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Title: European journal of heart failure Volume: 12 ISSN: 1879-0844 ISO Abbreviation: Eur. J. Heart Fail. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-25 Completed Date: 2010-08-20 Revised Date: 2011-06-08 |
Medline Journal Info:
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Nlm Unique ID: 100887595 Medline TA: Eur J Heart Fail Country: Netherlands |
Other Details:
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Languages: eng Pagination: 634-6 Citation Subset: IM |
Affiliation:
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Cardiovascular Center Aalst, Moorselbaan 164, Aalst, Belgium. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bundle-Branch Block
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therapy* Cardiac Pacing, Artificial* Female Heart Failure / etiology, physiopathology*, therapy* Humans Middle Aged Stroke Volume Ventricular Dysfunction, Left / therapy* |
| Comments/Corrections | |
Comment In:
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Eur J Heart Fail. 2010 Jun;12(6):527-9
[PMID:
20498266
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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