| Cardiac remodeling and failure after myocardial infarction. | |
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MedLine Citation:
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PMID: 7621314 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute myocardial infarction, particularly when it produces large transmural infarcts, can initiate complex changes in the structural and functional architecture of both infarcted and non-infarcted regions of the left ventricle, known as ventricular remodelling; these changes can profoundly affect left ventricular function and, consequently, clinical outcome and prognosis. Ventricular remodelling is a dynamic process with regional and global effects on wall thickness and composition and on chamber size, shape and function; it can include infarct extension, infarct expansion, regional and global distortion and ventricular dilatation. A systematic strategy for the [primary] prevention of cardiac remodeling should probably be applied as early as possible to all patients suffering acute myocardial infarction. A [secondary] prevention strategy should focus on the early identification and treatment of subsets of patients with evidence of cardiac remodeling, because later treatments have already been shown to be beneficial. Cardiologists must choose the strategy most appropriate for each individual patient. |
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Authors:
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G L Nicolosi |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of cardiovascular risk Volume: 1 ISSN: 1350-6277 ISO Abbreviation: J Cardiovasc Risk Publication Date: 1994 Dec |
Date Detail:
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Created Date: 1995-08-29 Completed Date: 1995-08-29 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9436980 Medline TA: J Cardiovasc Risk Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 310-3 Citation Subset: IM |
Affiliation:
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Department of Cardiology, A.R.C., Ospedale Civile, Pordenone, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiac Output, Low
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etiology*,
physiopathology,
prevention & control Heart Ventricles / pathology, physiopathology Humans Myocardial Infarction / complications*, pathology, physiopathology Prognosis Ventricular Dysfunction, Left / etiology*, physiopathology, prevention & control Ventricular Function, Left* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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