Document Detail


Cardiac output measurement by pulse dye densitometry in cardiac surgery.
MedLine Citation:
PMID:  16179040     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Summary The aim of this study was to compare the accuracy of pulse dye densitometry with that of bolus thermodilution cardiac output measurement in patients before and after elective coronary artery bypass grafting. Twenty-eight patients were studied. Agreement between mean thermodilution and pulse dye densitometry cardiac output values was assessed by Bland-Altman analysis. Preoperative median [range] cardiac output was 3.87 [2.37-6.0] l.min(-1) by thermodilution, and 3.11 [1.7-5.45] l.min(-1) by pulse dye densitometry using indocyanine green 5 mg. Pulse dye densitometry underestimated cardiac output (mean bias - 0.42 l.min(-1)); the limits of agreement were +/- 1.91 l.min(-1), and mean error was 50.3%, indicating low precision. Preoperative median [range] cardiac output was 3.85 [2.2-6.0] l.min(-1) for bolus thermodilution cardiac output and 4.2 [2.0-7.2] l.min(-1) for pulse dye densitometry using indocyanine green 20 mg. Mean bias was + 0.566 l.min(-1), the limits of agreement were +/- 2.51 l.min(-1) and mean error was 60.9%. Postoperative cardiac output data were not analysed because pulse dye densitometry signals were low or absent in > 50% of the patients. We conclude that pulse dye densitometry using indocyanine green 5 mg or 20 mg is inaccurate in anaesthetised patients before coronary artery bypass surgery and cannot be used after surgery because of a high incidence of low pulse dye densitometry signal amplitudes.
Authors:
W Baulig; E O Bernhard; D Bettex; D Schmidlin; E R Schmid
Publication Detail:
Type:  Comparative Study; Journal Article; Validation Studies    
Journal Detail:
Title:  Anaesthesia     Volume:  60     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-23     Completed Date:  2005-10-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  968-73     Citation Subset:  AIM; IM    
Affiliation:
Division of Cardiovascular Anaesthesia, University Hospital of Zürich, Rämistrasse 100, 8091 Zürich, Switzerland. werner.Baulig@usz.ch
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Anthropometry
Cardiac Output*
Contrast Media
Coronary Artery Bypass*
Densitometry
Female
Humans
Indocyanine Green / diagnostic use
Male
Middle Aged
Perioperative Care / methods
Reproducibility of Results
Thermodilution
Chemical
Reg. No./Substance:
0/Contrast Media; 3599-32-4/Indocyanine Green

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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