Document Detail

Cardiac output measured by uncalibrated arterial pressure waveform analysis by recently released software version 3.02 versus thermodilution in septic shock.
MedLine Citation:
PMID:  23154918     Owner:  NLM     Status:  Publisher    
To evaluate the 3.02 software version of the FloTrac/Vigileo™ system for estimation of cardiac output by uncalibrated arterial pressure waveform analysis, in septic shock. Nineteen consecutive patients in septic shock were studied. FloTrac/Vigileo™ measurements (COfv) were compared with pulmonary artery catheter thermodilution-derived cardiac output (COtd). The mean cardiac output was 7.7 L min(-1) and measurements correlated at r = 0.53 (P < 0.001, n = 314). In Bland-Altman plot for repeated measurements, the bias was 1.7 L min(-1) and 95 % limits of agreement (LA) were -3.0 to 6.5 L min(-1), with a %error of 53 %. The bias of COfv inversely related to systemic vascular resistance (SVR) (r = -0.54, P < 0.001). Above a SVR of 700 dyn s cm(-5) (n = 74), bias was 0.3 L min(-1) and 95 % LA were -1.6 to 2.2 L min(-1) (%error 32 %). Changes between consecutive measurements (n = 295) correlated at 0.67 (P < 0.001), with a bias of 0.1 % (95 % limits of agreement -17.5 to 17.0 %). All changes >10 % in both COtd and COfv (n = 46) were in the same direction. Eighty-five percent of the measurements were within the 30°-330° of the polar axis. COfv with the latest software still underestimates COtd at low SVR in septic shock. The tracking capacities of the 3.02 software are moderate-good when clinically relevant changes are considered.
Cornelis Slagt; Marcel A de Leeuw; Jan Beute; Emmy Rijnsburger; Martijn Hoeksema; Jan W R Mulder; Ignacio Malagon; A B Johan Groeneveld
Related Documents :
6498518 - Cardiovascular and t2-t4 dorsal horn cell responses to gallbladder distention in the cat.
12576968 - Should vasopressin replace adrenaline for endotracheal drug administration?
20622688 - Heart rate and pulse pressure variability are associated with intractable intracranial ...
24356578 - Alteration of mevalonate pathway related enzyme expressions in pressure overload-induce...
14649338 - The 'tei-index' is preload dependent and can be measured by transoesophageal echocardio...
2929368 - Influences of the sympatho-adrenal system on gastric motility and acid secretion and on...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-15
Journal Detail:
Title:  Journal of clinical monitoring and computing     Volume:  -     ISSN:  1573-2614     ISO Abbreviation:  J Clin Monit Comput     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9806357     Medline TA:  J Clin Monit Comput     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Zaans Medical Centre, Koningin Julianaplein 58, Postbus 210, 1500 EE, Zaandam, The Netherlands,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A Carborane-Derivative "Click" Reaction under Heterogeneous Conditions for the Synthesis of a Promis...
Next Document:  Intrinsically Copper-64-Labeled Organic Nanoparticles as Radiotracers.