Document Detail

Cardiac output in asymptomatic primary hyperparathyroidism: a stigma of early cardiovascular dysfunction?
MedLine Citation:
PMID:  8912086     Owner:  NLM     Status:  MEDLINE    
The resting cardiac output pre- and postoperatively in 10 patients with asymptomatic primary hyperparathyroidism has been studied. All patients had normal renal function and arterial blood pressure without a previous history of cardiovascular disease. Ten normotensive patients with a non-toxic goitre awaiting thyroidectomy were studied as controls. The mean cardiac output of the hyperparathyroid patients was 7.2 l/minute (range 5.3-8.9) and of the control group 5.8 l/minute (range 5.2-6.3). Following a successful parathyroidectomy with return of the serum calcium to normal, the mean cardiac output was 6.3 l/minute (range 4.9-7.8) (p < 0.04). In 8 of the 10 patients there was a fall in the cardiac output following surgery; in 2 there was an increase. These results suggest that hyperparathyroid patients often have an elevated cardiac output which may fall following a successful parathyroidectomy.
S N Georgiannos; B J Jenkins; A W Goode
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International surgery     Volume:  81     ISSN:  0020-8868     ISO Abbreviation:  Int Surg     Publication Date:    1996 Apr-Jun
Date Detail:
Created Date:  1997-02-19     Completed Date:  1997-02-19     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0043524     Medline TA:  Int Surg     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  171-3     Citation Subset:  IM    
Royal London Hospital Medical College, University of London, Academic Surgical Unit, Whitechapel, UK.
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MeSH Terms
Adenoma / complications,  surgery
Cardiac Output*
Echocardiography, Doppler
Hyperparathyroidism / etiology,  physiopathology*,  surgery
Middle Aged
Parathyroid Neoplasms / complications,  surgery

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