Document Detail

Cardiac myxomas--clinical spectrum and outcome.
MedLine Citation:
PMID:  16899175     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe the characteristics and outcome of patients with cardiac myxomas. DESIGN: A case series. PLACE AND DURATION OF STUDY: The Aga Khan University Hospital (AKUH), from 1999 to 2004. PATIENTS AND METHODS: All patients diagnosed and managed as having cardiac myxomas at AKUH, during a period of six years (1999-2004) were included. Data was collected by reviewing clinical records. Follow-up data was collected from the clinical records and by a telephone interview where required. RESULTS: Out of 15 patients who were diagnosed to have cardiac myxomas, complete information was available in 14 patients. There was a female predominance (64%) with a mean age of 47 years. About two-thirds (71%) had symptom of dyspnoea. Half of the patients (50%) had neurological symptoms at presentation. Constitutional symptoms were present in 36% of patients. About two-third of patients (71%) had positive findings on cardiac auscultation. None of the patients had any rhythm abnormalities on the ECG. Diagnosis was made by transthoracic echocardiography in all patients. All of the tumors were located in the left atrium, and majority (64%) were attached to the interatrial septum. All patients were advised surgical treatment, however, only 8 (57%) were operated upon. Outcome was good in those who were operated upon, with no peri and postoperative mortality. CONCLUSIONS: Cardiac myxomas are a rare, but potentially curable form of heart disease. They occur in a wide range of age groups with a female predominance. Dyspnea is the most common clinical feature followed by embolic complications. Left atrium is the most common site of location. Surgical excision is a safe and effective procedure.
Fateh Ali Tipoo Sultan; Ali Syed; Khawar Kazmi; Sajid Dhakam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP     Volume:  16     ISSN:  1022-386X     ISO Abbreviation:  J Coll Physicians Surg Pak     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-10     Completed Date:  2006-11-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606447     Medline TA:  J Coll Physicians Surg Pak     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  501-3     Citation Subset:  IM    
Department of Medicine, Section of Cardiology, The Aga Khan University Hospital, Karachi.
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MeSH Terms
Cardiac Surgical Procedures
Follow-Up Studies
Heart Atria / pathology,  surgery
Heart Neoplasms* / diagnosis,  surgery
Heart Septum / pathology,  surgery
Middle Aged
Mitral Valve / pathology,  surgery
Myxoma* / diagnosis,  surgery
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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