Document Detail

Cardiac myxoma induced paraneoplastic syndromes: A review of the literature.
MedLine Citation:
PMID:  23122392     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Atrial myxomas are the most common benign tumors of the heart and may present with a wide variety of symptoms. Although 45% of patients present with neurological symptoms, a diverse range of systemic symptoms also occur.
METHODS: A systemic review of the literature related to the diagnosis, treatment, pathogenesis, and symptoms associated with atrial myxomas was performed.
RESULTS: Here we summarize the current state of understanding about myxoma pathogenesis and treatments are described. We review the common and rare local and systemic effects of myxomas. Additionally, we review the paraneoplastic and metastatic potential of myxomas.
CONCLUSIONS: A better understanding of the diverse disease presentations, paraneoplastic syndromes, and side effects of cytokine abnormalities stemming from myxomas will aid the physician in earlier detection and monitoring of disease recurrence.
Marcus Smith; Muhammad A Chaudhry; Pedro Lozano; Mary Beth Humphrey
Publication Detail:
Type:  Journal Article     Date:  2012-06-30
Journal Detail:
Title:  European journal of internal medicine     Volume:  23     ISSN:  1879-0828     ISO Abbreviation:  Eur. J. Intern. Med.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9003220     Medline TA:  Eur J Intern Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  669-73     Citation Subset:  IM    
Copyright Information:
Published by Elsevier B.V.
Department of Internal Medicine, Section of Cardiovascular Disease, University of Oklahoma Health Sciences Center, Oklahoma City, USA. Electronic address:
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