Document Detail

Cardiac metastasis of hepatocellular carcinoma in a young non-cirrhotic patient, to the left ventricle.
MedLine Citation:
PMID:  22481459     Owner:  NLM     Status:  MEDLINE    
Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver.(1,2) The most common extrahepatic metastatic sites are lung, abdominal lymph nodes and bone, while its cardiac metastasis is rare.(2,3) Metastasis of HCC into the cardiac cavity is mostly caused by direct tumor invasion of vena cava inferior with continuous extension into the right cardiac cavity.(4,5) Right heart metastasis without invasion of inferior vena cava, which may be caused by hematogenous spread of cancer cells, is rarely reported.(6,7) This paper announces an unusual case of isolated involvement of left ventricle (LV) together with myocardial invasion of HCC. Our patient is known to be the first case with isolated HCC metastasis to the left ventricle. Strikingly, the patient was young and non-cirrhotic with negative serum HBsAg, and anti-HCV results.
Ebru Tastekin; Ufuk Usta; Turan Ege; Gokhan Kazindir; Ali Kemal Kutlu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of hepatology     Volume:  11     ISSN:  1665-2681     ISO Abbreviation:  Ann Hepatol     Publication Date:    2012 May-Jun
Date Detail:
Created Date:  2012-04-06     Completed Date:  2012-08-23     Revised Date:  2013-05-16    
Medline Journal Info:
Nlm Unique ID:  101155885     Medline TA:  Ann Hepatol     Country:  Mexico    
Other Details:
Languages:  eng     Pagination:  392-4     Citation Subset:  IM    
Trakya University Medical Faculty, Department of Pathology, Edirne, Turkey.
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MeSH Terms
Biopsy, Needle
Carcinoma, Hepatocellular / pathology*
Fatal Outcome
Heart Neoplasms / radiography,  secondary*
Heart Ventricles* / pathology,  radiography
Liver Neoplasms / pathology*
Multiple Organ Failure / mortality
Tomography, X-Ray Computed
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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