| Cardiac metabolism in hypertrophy and heart failure: implications for therapy. | |
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MedLine Citation:
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PMID: 23124940 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The heart consumes huge amounts of energy to fulfil its function as a relentless pump. A highly sophisticated system of energy generation based on flexibility of substrate use and efficient energy production, effective energy sensing and energy transfer ensures function of the healthy heart across a range of physiological situations. In left ventricular hypertrophy and heart failure, these processes become disturbed, leading as will be discussed to impaired cardiac energetic status and to further impairment of cardiac function. These metabolic disturbances form a potential target for therapy. |
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Authors:
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N Siddiqi; S Singh; R Beadle; D Dawson; M Frenneaux |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-4 |
Journal Detail:
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Title: Heart failure reviews Volume: - ISSN: 1573-7322 ISO Abbreviation: Heart Fail Rev Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-5 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9612481 Medline TA: Heart Fail Rev Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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School of Medicine and Dentistry, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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