Document Detail

Cardiac magnetic resonance in the study of neonatal haemodynamics.
MedLine Citation:
PMID:  20970397     Owner:  NLM     Status:  MEDLINE    
Circulatory failure plays a key role in the pathogenesis of mortality and key morbidity such as cerebral injury in the preterm infant. However awareness of the pathophysiology of circulatory failure itself is not well understood. Similarly there is significant uncertainty over optimal treatment approaches, particularly for inotropic therapies. Current uncertainties are perpetuated by difficulties with accurately assessing circulatory function. Cardiac magnetic resonance (CMR) imaging has produced significant advances in understanding of adult circulatory function, and acts as a powerful biomarker for interventional studies. Although routine circulatory assessment by CMR in the neonatal population is not currently a realistic goal, it could provide insights into pathophysiology; and act as an outcome measure in clinical trials in small numbers of infants in specialist centres. This review focuses on available CMR techniques, scope for use in the neonatal population, and our initial experience with the technique.
Alan M Groves
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Seminars in fetal & neonatal medicine     Volume:  16     ISSN:  1878-0946     ISO Abbreviation:  Semin Fetal Neonatal Med     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2010-12-28     Completed Date:  2011-05-24     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  101240003     Medline TA:  Semin Fetal Neonatal Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  36-41     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
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MeSH Terms
Cardiovascular Physiological Phenomena*
Cardiovascular System
Coronary Vessels / physiology*
Hemodynamics / physiology
Infant, Newborn
Infant, Premature / physiology*
Magnetic Resonance Imaging / methods*
Grant Support
G0701896//Medical Research Council; //Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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