Document Detail

Cardiac magnetic resonance imaging after stage I Norwood operation for hypoplastic left heart syndrome.
MedLine Citation:
PMID:  16301358     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: After the Norwood operation, a patient's suitability for proceeding to a bidirectional cavopulmonary connection (BCPC) is assessed by a combination of echocardiography and diagnostic cardiac catheterization. In this study, we describe the results of 37 patients who underwent cardiovascular magnetic resonance (MR) assessment before BCPC. METHODS AND RESULTS: Cardiovascular MR and echocardiography were performed in 37 infants with hypoplastic left heart syndrome before BCPC, and the findings were compared with surgical findings. MR assessment of ventricular function and valvar regurgitation were compared with echocardiography. MR exhibited high sensitivity and specificity for identification of neoaortic (sensitivity 86%, specificity 97%) and left pulmonary artery (sensitivity 100%, specificity 94%) obstruction. Echocardiography exhibited poor sensitivity for identification of vascular stenosis. The mean right ventricular ejection fraction calculated from the MR data was 50+/-10%. There was general agreement between MR and echocardiographic measures of ventricular function, although patients with good function on echocardiography demonstrated a wide range of ejection fractions. There was good agreement between MR and echocardiography for identification of valvar regurgitation. CONCLUSIONS: Cardiovascular MR can be used to define ventricular and valvar function and vascular anatomy in infants with hypoplastic left heart syndrome after the Norwood operation. We have shown how this information can be used to plan the BCPC and identify any revisions or additional valvar surgery.
Vivek Muthurangu; Andrew M Taylor; Sanjeet R Hegde; Robert Johnson; Robert Tulloh; John M Simpson; Shakeel Qureshi; Eric Rosenthal; Edward Baker; David Anderson; Reza Razavi
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Circulation     Volume:  112     ISSN:  1524-4539     ISO Abbreviation:  Circulation     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-11-22     Completed Date:  2006-02-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3256-63     Citation Subset:  AIM; IM    
Cardiac MR Research Group, Division of Imaging Sciences, King's College London, United Kingdom.
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MeSH Terms
Aorta / physiology
Aortic Diseases / pathology,  surgery,  ultrasonography
Cardiac Surgical Procedures*
Gadolinium / diagnostic use
Heart Valve Diseases / pathology,  surgery,  ultrasonography
Heart Valves / physiology
Hypoplastic Left Heart Syndrome / pathology*,  surgery*,  ultrasonography
Infant, Newborn
Magnetic Resonance Imaging / methods*
Predictive Value of Tests
Pulmonary Artery / pathology,  surgery
Sensitivity and Specificity
Stroke Volume
Reg. No./Substance:
Erratum In:
Circulation. 2006 Feb 7;113(5):e70

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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