Document Detail

Cardiac magnetic resonance detection of left ventricular thrombus in acute myocardial infarction.
MedLine Citation:
PMID:  23425009     Owner:  NLM     Status:  In-Data-Review    
Introduction: Left ventricular thrombosis (LVT) is a possible complication of acute myocardial infarction. Aim of our study was to evaluate incidence and clinical characteristics of patients with LVT after ST elevation myocardial infarction (STEMI) using contrast- enhanced magnetic resonance (CMR).Methods and Results: In a prospective cohort of 36 consecutive patients with STEMI acutely reperfused with primary percutaneous coronary intervention, CMR was performed within one week. LVT was found in 7 patients (19%), and was located in left ventricle apex or adherent to antero-septum. Compared to the rest of population patients with LVT have lower ejection fraction (38 ± 7% versus 51 ± 6%, P = 0.009), larger left ventricle end systolic volume (95.8 ± 19 ml versus 68.9 ± 19 ml, P = 0.02), higher time to reperfusion (9.3 ± 7.2 versus 5 ± 3.6, P = 0.03) and left anterior descending artery was constantly involved (100% versus 41 %, P = 0.06). In 5 cases the LVT was also detected by echocardiography, however, in 2 cases it was missed. Conclusions: The incidence of LVT after STEMI is not negligible and was accurately detected by CMR. Localization of myocardial infarction, time to reperfusion, ejection fraction and left ventricle end systolic volume are the most important predictors of left ventricle thrombus formation.
Chiara Lanzillo; Mauro Di Roma; Alessandro Sciahbasi; Monia Minati; Luciano Maresca; Gianluca Pendenza; Enrico Romagnoli; Francesco Summaria; Roberto Patrizi; Marco Di Luozzo; Paolo Preziosi; Ernesto Lioy; Francesco Romeo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acute cardiac care     Volume:  15     ISSN:  1748-295X     ISO Abbreviation:  Acute Card Care     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101276603     Medline TA:  Acute Card Care     Country:  England    
Other Details:
Languages:  eng     Pagination:  11-6     Citation Subset:  IM    
Cardiology Department, Policlinico Casilino , Rome , Italy.
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