Document Detail

Cardiac limitation to maximal oxygen transport and changes in components after jogging across the US.
MedLine Citation:
PMID:  1213977     Owner:  NLM     Status:  MEDLINE    
Observations were made before and 3-5 days after prolonged endurance jogging an average of 42 miles/day, 6 days/wk for 2.5 mo by a young male adult who voluntarily initiated a run across the United States. Both arterial PO2 and lactic acid increased. In each instance, the first limitation in circulatory delivery of oxygen was a plateau in stroke volume and cardiac output. Afterward, pulse deficit and systemic arterial pressure fell with exercise and heart rate accelerated. Although there was no change in oxygen transport (Q X CAO2), a reduction in stroke volume was exactly balanced by a rise in arterial oxygen content. Vital capacity, residual volume, and total lung capacity and diffusion capacity for carbon monoxide, hematocrit, and red cell mass increased, while plasma volume diminished and heart size and total blood volume were unchanged.
R A Bruce; F Kusumi; B H Culver; J Butler
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of applied physiology     Volume:  39     ISSN:  0021-8987     ISO Abbreviation:  J Appl Physiol     Publication Date:  1975 Dec 
Date Detail:
Created Date:  1976-04-27     Completed Date:  1976-04-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376576     Medline TA:  J Appl Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  958-64     Citation Subset:  IM; S    
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MeSH Terms
Blood Pressure
Cardiac Output*
Heart Rate
Oxygen / blood*
Time Factors
United States
Reg. No./Substance:

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