Document Detail

Cardiac lesions in non-specific aorto-arteritis. An autopsy study.
MedLine Citation:
PMID:  7989078     Owner:  NLM     Status:  MEDLINE    
Autopsy data of 58 cases (1958-1986) was analysed for cardiac lesions. The cases were divided into 2 groups; paediatric (23) and adult (35). The heart was normal in 8.7% and 20.5% of the above groups respectively. Rest of the cases showed left ventricular hypertrophy with variable dilatation. Obstructive lesion in the aorta and or renal arteries was present in 91.3% of paediatric and 80.0% of adult cases. Congestive cardiac failure was very common in paediatric group (60.8%) and was not seen in absence of obstructive lesion in the aorta or renal arteries. Histologically the aortic lesion was healed in 70% and 50% of paediatric and adult cases. The commonest additional lesion found, was coronary artery involvement in 11 cases (17%). Ostial stenosis was noted in 7 cases, including 2 in paediatric age group. Epicardial coronaries were involved in 4 cases with infarcts in 4. Aortic incompetence was rare (3.4%). Associated rheumatic mitral stenosis was seen in 2 and healed infective endocarditis in one. Histologically apart from the above mentioned lesions the myocardium showed essentially a response to hypertension. Focal lymphocytic infiltration was seen in 2 children and tuberculosis myocarditis in 3 adults. No case of any other type of myocarditics or cardiomyopathy was seen. In conclusion hypertension and coronary artery disease are the main factors responsible for myocardial failure but additional related or unrelated factors were present in 15.0% cases.
S G Kinare
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian heart journal     Volume:  46     ISSN:  0019-4832     ISO Abbreviation:  Indian Heart J     Publication Date:    1994 Mar-Apr
Date Detail:
Created Date:  1995-01-10     Completed Date:  1995-01-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0374675     Medline TA:  Indian Heart J     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  65-9     Citation Subset:  IM    
Seth G.S. Medical College, Bombay.
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MeSH Terms
Aorta / pathology
Child, Preschool
Coronary Vessels / pathology
Heart Diseases / etiology,  pathology*
Middle Aged
Myocardium / pathology
Renal Artery / pathology
Takayasu Arteritis / complications,  pathology*

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