| Cardiac function and oxygen balance in septic patients during continuous hemofiltration. | |
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MedLine Citation:
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PMID: 9681156 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this work was to study hemodynamic, oximetric and metabolic parameters in septic patients during continuous hemofiltration, in order to determine whether the changes in hemodynamic parameters can influence the oxygen utilization in peripheral tissues. 29 multiple organ failure patients with septic shock were studied during the first 48 h of continuous hemofiltration: 18 were submitted to CAVH and 11 patients were treated with CAVHD to correct ARF and fluid overload. Our data show that RVEF improves and REDVI reduces progressively during treatment, together with a significant reduction of the cardiac index after 48 h of CAVH(D). There were no significant variations in oxygen tissue parameters, while plasma lactate was reduced significantly. In conclusion, our data confirm that continuous hemofiltration may be useful in septic patients to correct fluid overload and ARF, without affecting hemodynamic stability and oxygen balance. Moreover, in septic patients, this technique improves hemodynamics, reduces the filling pressure in the right heart and reduces hyperdynamic response as CI and SVRI, without any negative effects on O2 balance. |
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Authors:
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C Meloni; M Morosetti; F Turani; G Palombo; L Meschini; E Zupancich; M Taccone-Gallucci; S Di Giulio; C U Casciani |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Blood purification Volume: 16 ISSN: 0253-5068 ISO Abbreviation: Blood Purif. Publication Date: 1998 |
Date Detail:
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Created Date: 1998-10-13 Completed Date: 1998-10-13 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8402040 Medline TA: Blood Purif Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 140-6 Citation Subset: IM |
Affiliation:
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Institute of Tissue Typing, NCR, L'Aquila, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Hemodynamics* Hemofiltration* Humans Male Middle Aged Oxygen / blood* Oxygen Consumption Shock, Septic / blood, physiopathology*, therapy* |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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