| Cardiac function after alcohol ingestion in patients with ischemic heart disease and cardiomyopathy: a controlled study. | |
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MedLine Citation:
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PMID: 3358819 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty male patients with ischemic heart disease and cardiomyopathy entered a controlled study of the acute effects of alcohol on cardiac function evaluated by right heart catheterization. Twenty patients, nine with angina pectoris and 11 with congestive heart failure, were studied during alcohol intoxication, and ten patients, five with angina pectoris and five with heart failure, served as a control group. The mean serum ethanol concentration in the alcohol group was 93 mg/100 ml (S.D. 17). The systemic arterial blood pressure was reduced by 6% in the alcohol group, P less than 0.05 compared with the control group. No significant changes occurred in the central venous pressure, the pulmonary artery pressure, the pulmonary capillary wedge pressure, or in cardiac output, stroke volume and total peripheral resistance. Alcohol intake in moderate doses has no measurable effect on pulmonary blood pressures or cardiac output in patients with ischemic heart disease and cardiomyopathy. Such an effect may, however, be masked by a reduction of afterload. |
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Authors:
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H Kelbaek; L Heslet; K Skagen; O Munck; N J Christensen; J Godtfredsen |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Alcohol and alcoholism (Oxford, Oxfordshire) Volume: 23 ISSN: 0735-0414 ISO Abbreviation: Alcohol Alcohol. Publication Date: 1988 |
Date Detail:
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Created Date: 1988-06-09 Completed Date: 1988-06-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8310684 Medline TA: Alcohol Alcohol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 17-21 Citation Subset: IM |
Affiliation:
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Department of Clinical Physiology and Nuclear Medicine, Herlev Hospital, University of Copenhagen, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Alcoholic Intoxication / complications Cardiac Output / drug effects Ethanol / pharmacology* Heart / drug effects* Heart Diseases / complications, physiopathology* Heart Rate / drug effects Humans Male Middle Aged Stroke Volume / drug effects |
| Chemical | |
Reg. No./Substance:
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64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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