Document Detail

Cardiac failure and multiple organ dysfunction syndrome in a patient with endocrine adenomatosis.
MedLine Citation:
PMID:  12366515     Owner:  NLM     Status:  MEDLINE    
In this case report, we present the successful therapy of severe cardiac failure in pituitary adrenal insufficiency. A previously healthy 56-year-old-man in pituitary coma due to an atypical variant of multiple endocrine adenomatosis (pituitary adenoma and pheochromocytoma) suffered from cardiac failure resistant to catecholamine and standard hydrocortisone therapy. After two bolus injections of dexamethasone (2 x 24 mg) mean arterial pressure and cardiac function dramatically improved, probably due to restoration of permissive effects on catecholamine action and reversal of pathophysiological mechanisms of cardiac failure. We conclude that in patients with severe cardiovascular failure in pituitary coma the administration of potent glucocorticoids may be more effective in reversing cardiovascular failure than standard dosages of hydrocortisone.
M W Dünser; A J Mayr; R Gasser; M Rieger; B Friesenecker; W R Hasibeder
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  46     ISSN:  0001-5172     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-10-07     Completed Date:  2002-12-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  1161-4     Citation Subset:  IM    
Division of General and Surgical Intensive Care Medicine, Department of Anesthesia and Critical Care Medicine, the Leopold Franzens University of Innsbruck, Innsbruck, Austria.
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MeSH Terms
Adenoma / complications*,  diagnosis
Adrenal Gland Neoplasms / complications*,  diagnosis
Cardiac Output, Low / complications*
Middle Aged
Multiple Endocrine Neoplasia / complications,  diagnosis
Multiple Organ Failure / etiology*
Pheochromocytoma / complications*,  diagnosis
Pituitary Neoplasms / complications*,  diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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